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Molecular Cancer Therapeutics|August 19, 2016
BCL2 Inhibitors as Anticancer Drugs: A Plethora of Misleading BH3 MimeticsRyan S Soderquist, Alan Eastman
The Journal of Biological Chemistry|April 30, 2014
Gossypol increases expression of the pro-apoptotic BH3-only protein NOXA through a novel mechanism involving phospholipase A2, cytoplasmic calcium, and endoplasmic reticulum stressRyan S Soderquist, Alexey V Danilov, Alan Eastman
Nucleic Acids Research|December 17, 2013
Genetic analysis of the Replication Protein A large subunit family in Arabidopsis reveals unique and overlapping roles in DNA repair, meiosis and DNA replicationBehailu B Aklilu, Ryan S Soderquist, Kevin M Culligan
Cell Death & Disease|February 24, 2019
Confounding off-target effects of BH3 mimetics at commonly used concentrations: MIM1, UMI-77, and A-1210477David J Mallick, Ryan S Soderquist, Darcy Bates, et al.
Nature Communications|March 15, 2023
Executioner caspases restrict mitochondrial RNA-driven Type I IFN induction during chemotherapy-induced apoptosisShane T Killarney, Rachel Washart, Ryan S Soderquist, et al.
The Journal of Biological Chemistry|June 2, 2011
Multiple BH3 mimetics antagonize antiapoptotic MCL1 protein by inducing the endoplasmic reticulum stress response and up-regulating BH3-only protein NOXATina C Albershardt, Bethany L Salerni, Ryan S Soderquist, et al.
Molecular Cancer Therapeutics|June 24, 2011
Discovery of a small molecule targeting IRA2 deletion in budding yeast and neurofibromin loss in malignant peripheral nerve sheath tumor cellsMatthew Wood, Melissa Rawe, Gunnar Johansson, et al.
Plos One|November 26, 2015
Cyclin-Dependent Kinase Inhibitor P1446A Induces Apoptosis in a JNK/p38 MAPK-Dependent Manner in Chronic Lymphocytic Leukemia B-CellsCody Paiva, J Claire Godbersen, Ryan S Soderquist, et al.
Nature Communications|August 31, 2018
Systematic mapping of BCL-2 gene dependencies in cancer reveals molecular determinants of BH3 mimetic sensitivityRyan S Soderquist, Lorin Crawford, Esther Liu, et al.
Science Advances|September 14, 2019
Genomically informed small-molecule drugs overcome resistance to a sustained-release formulation of an engineered death receptor agonist in patient-derived tumor modelsMandana T Manzari, Gray R Anderson, Kevin H Lin, et al.
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