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Biochemical and Biophysical Research Communications|June 19, 2015
Spermidine and Ca(2+), but not Na(+), can permeate NMDA receptors consisting of GluN1 and GluN2A or GluN2B in the presence of Mg(2+)Tadao Hirose, Ryotaro Saiki, Yuki Yoshizawa, et al.
Bioorganic & Medicinal Chemistry|December 27, 2017
Design, synthesis, and evaluation of polyamine-memantine hybrids as NMDA channel blockersTakuya Kumamoto, Marie Nakajima, Reina Uga, et al.
Atherosclerosis|December 3, 2015
Toxic acrolein production due to Ca(2+) influx by the NMDA receptor during strokeMizuho Nakamura, Takeshi Uemura, Ryotaro Saiki, et al.
Journal of Neurochemistry|June 15, 2013
Acrolein stimulates the synthesis of IL-6 and C-reactive protein (CRP) in thrombosis model mice and cultured cellsRyotaro Saiki, Daisuke Hayashi, Yukiko Ikuo, et al.
The International Journal of Biochemistry & Cell Biology|March 19, 2013
Role of polyamines at the G1/S boundary and G2/M phase of the cell cycleTomoko Yamashita, Kazuhiro Nishimura, Ryotaro Saiki, et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry|August 25, 2015
Increase in acrolein-conjugated immunoglobulins in saliva from patients with primary Sjögren's syndromeTadao Hirose, Ryotaro Saiki, Takeshi Uemura, et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry|December 28, 2014
Distinguishing mild cognitive impairment from Alzheimer's disease with acrolein metabolites and creatinine in urineMadoka Yoshida, Kyohei Higashi, Kyoshiro Kuni, et al.
Journal of Alzheimer'S Disease : JAD|July 4, 2012
Increased protein-conjugated acrolein and amyloid-β40/42 ratio in plasma of patients with mild cognitive impairment and Alzheimer's diseaseMasaaki Waragai, Madoka Yoshida, Mutsumi Mizoi, et al.
The Journal of Pharmacology and Experimental Therapeutics|June 30, 2012
Structural changes of regulatory domain heterodimer of N-methyl-D-aspartate receptor subunits GluN1 and GluN2B through the binding of spermine and ifenprodilHideyuki Tomitori, Akiko Suganami, Ryotaro Saiki, et al.
Biochemical and Biophysical Research Communications|December 29, 2010
Brain infarction correlates more closely with acrolein than with reactive oxygen speciesRyotaro Saiki, Hyerim Park, Itsuko Ishii, et al.
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