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Biochemical and Biophysical Research Communications|April 12, 2002
BAY 41-2272 activates two isoforms of nitric oxide-sensitive guanylyl cyclaseMarkus Koglin, Johannes-Peter Stasch, Sönke Behrends
Biochemical Pharmacology|February 13, 2019
A novel soluble guanylyl cyclase activator, BR 11257, acts as a non-stabilising partial agonist of sGCChristin Elgert, Anne Rühle, Peter Sandner, et al.
Journal of Pharmaceutical and Biomedical Analysis|February 8, 2020
Thermal shift assay: Strengths and weaknesses of the method to investigate the ligand-induced thermostabilization of soluble guanylyl cyclaseChristin Elgert, Anne Rühle, Peter Sandner, et al.
Analytical and Bioanalytical Chemistry|December 6, 2021
Combination of strong anion exchange liquid chromatography with microchip capillary electrophoresis sodium dodecyl sulfate for rapid two-dimensional separations of complex protein mixturesHolger Zagst, Christin Elgert, Sönke Behrends, et al.
European Journal of Pharmacology|March 27, 2025
Discovery of the first isoform-specific sGC activator: Selective activation of GC-1 by runcaciguatSvenja Stomberg, Anne Rühle, Theresa Wittrien, et al.
Neurochemistry International|August 18, 2004
Cerebral expression of the alpha2-subunit of soluble guanylyl cyclase is linked to cerebral maturation and sensory pathway refinement during postnatal developmentHans-J Bidmon, Jutta Starbatty, Boris Görg, et al.
Hepatology (Baltimore, Md.)|October 24, 2002
Region selective alterations of soluble guanylate cyclase content and modulation in brain of cirrhotic patientsRegina Corbalán, Nicolas Chatauret, Sönke Behrends, et al.
European Journal of Pharmacology|May 25, 2020
Tyrosine 135 of the β1 subunit as binding site of BAY-543: Importance of the Y-x-S-x-R motif for binding and activation by sGC activator drugsAnne Rühle, Christin Elgert, Michael G Hahn, et al.
The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society|October 5, 2002
The expression pattern of nitric oxide-sensitive guanylyl cyclase in the rat heart changes during postnatal developmentSönke Behrends, Andrea Mietens, Jörg Kempfert, et al.
Biochemical Pharmacology|January 6, 2025
Runcaciguat activates soluble guanylyl cyclase via the histidine essential for heme binding and nitric oxide activationTheresa Wittrien, Anne Rühle, Christin Elgert, et al.
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