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Cancer Gene Therapy|January 1, 1997
Coexpression of a multidrug resistance gene (MDR1) and herpes simplex virus thymidine kinase gene in a bicistronic retroviral vector Ha-MDR-IRES-TK allows selective killing of MDR1-transduced human tumors transplanted in nude miceY Sugimoto, S Sato, S Tsukahara, et al.
Molecular Cell|October 13, 2000
Reconstitution of an ATM-dependent checkpoint that inhibits chromosomal DNA replication following DNA damageV Costanzo, K Robertson, C Y Ying, et al.
Biochemistry|October 31, 1995
Bacterial expression of the linker region of human MDR1 P-glycoprotein and mutational analysis of phosphorylation sitesT C Chambers, U A Germann, M M Gottesman, et al.
Cancer Research|June 1, 1987
Isolation of human KB cell lines resistant to epidermal growth factor-Pseudomonas exotoxin conjugatesR M Lyall, J L Hwang, C Cardarelli, et al.
Japanese Journal of Cancer Research : Gann|November 1, 1989
Detection of multidrug resistance (MDR1) gene RNA expression in human tumors by a sensitive ribonuclease protection assayK Ueda, Y Yamano, N Kioka, et al.
Biochemistry|September 30, 1998
Structural flexibility of the linker region of human P-glycoprotein permits ATP hydrolysis and drug transportC A Hrycyna, L E Airan, U A Germann, et al.
Molecular Pharmacology|October 1, 1991
Fluorescent verapamil derivative for monitoring activity of the multidrug transporterI H Lelong, A P Guzikowski, R P Haugland, et al.
The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society|July 1, 1989
The multidrug transporter: rapid modulation of efflux activity monitored in single cells by the morphologic effects of vinblastine and daunomycinP L Konen, S J Currier, A V Rutherford, et al.
The Journal of Biological Chemistry|December 24, 2002
Studies with novel Pdr5p substrates demonstrate a strong size dependence for xenobiotic effluxJohn Golin, Suresh V Ambudkar, Michael M Gottesman, et al.
Journal of Inorganic Biochemistry|May 30, 2015
Reduced accumulation of platinum drugs is not observed in drug-resistant ovarian cancer cell lines derived from cisplatin-treated patientsMarina Stukova, Matthew D Hall, Samantha D Tsotsoros, et al.
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