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Journal of Medicinal Chemistry|October 29, 2000
Discovery of a potent, orally bioavailable beta(3) adrenergic receptor agonist, (R)-N-[4-[2-[[2-hydroxy-2-(3-pyridinyl)ethyl]amino]ethyl]phenyl]-4-[4 -[4-(trifluoromethyl)phenyl]thiazol-2-yl]benzenesulfonamideR J Mathvink, J S Tolman, D Chitty, et al.Bioorganic & Medicinal Chemistry Letters|July 11, 2000
Synthesis and SAR of benzyl and phenoxymethylene oxadiazole benzenesulfonamides as selective beta3 adrenergic receptor agonist antiobesity agentsT Biftu, D D Feng, G B Liang, et al.Bioorganic & Medicinal Chemistry Letters|April 14, 1999
Human beta3 adrenergic receptor agonists containing imidazolidinone and imidazolone benzenesulfonamidesE M Naylor, E R Parmee, V J Colandrea, et al.Bioorganic & Medicinal Chemistry Letters|April 14, 1999
Human beta3 adrenergic receptor agonists containing cyclic ureidobenzenesulfonamidesE R Parmee, E M Naylor, L Perkins, et al.Nature Genetics|September 6, 2000
Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body massA S Chen, D J Marsh, M E Trumbauer, et al.Bioorganic & Medicinal Chemistry Letters|January 5, 1999
3-Pyridyloxypropanolamine agonists of the beta 3 adrenergic receptor with improved pharmacokinetic propertiesA E Weber, H O Ok, R F Alvaro, et al.Journal of Medicinal Chemistry|March 29, 2000
Phosphorylated morpholine acetal human neurokinin-1 receptor antagonists as water-soluble prodrugsJ J Hale, S G Mills, M MacCoss, et al.The Journal of Clinical Investigation|June 17, 1998
A selective human beta3 adrenergic receptor agonist increases metabolic rate in rhesus monkeysM H Fisher, A M Amend, T J Bach, et al.Journal of Medicinal Chemistry|April 13, 2001
A potent, nonpeptidyl 1H-quinolone antagonist for the gonadotropin-releasing hormone receptorR J DeVita, T F Walsh, J R Young, et al.Pageof 10