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The American Journal of Pathology
|
November 15, 2011
BACE2 expression increases in human neurodegenerative disease
Christopher J Holler, Robin L Webb, Ashley L Laux, et al.
ACS Medicinal Chemistry Letters
|
February 20, 2018
Discovery and in Vitro Optimization of 3-Sulfamoylbenzamides as ROMK Inhibitors
Matthew F Sammons, Sujay V Kharade, Kevin J Filipski, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 9, 2023
Discovery of PFI-6, a small-molecule chemical probe for the YEATS domain of MLLT1 and MLLT3
Brigitt Raux, Karly A Buchan, James Bennett, et al.
ACS Medicinal Chemistry Letters
|
December 1, 2015
Discovery of an in Vivo Tool to Establish Proof-of-Concept for MAP4K4-Based Antidiabetic Treatment
Mark Ammirati, Scott W Bagley, Samit K Bhattacharya, et al.
RSC Medicinal Chemistry
|
March 22, 2024
Chemical tools for the Gid4 subunit of the human E3 ligase C-terminal to LisH (CTLH) degradation complex
Aliakbar Khalili Yazdi, Sumera Perveen, Cheng Dong, et al.
Medchemcomm
|
August 16, 2018
Small structural changes of the imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitors produce an improved safety profile
K Futatsugi, K Huard, D W Kung, et al.
Journal of Medicinal Chemistry
|
September 10, 2020
Discovery of PF-06835919: A Potent Inhibitor of Ketohexokinase (KHK) for the Treatment of Metabolic Disorders Driven by the Overconsumption of Fructose
Kentaro Futatsugi, Aaron C Smith, Meihua Tu, et al.
Journal of Medicinal Chemistry
|
October 29, 2015
Discovery of 2-(6-(5-Chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide (PF-06282999): A Highly Selective Mechanism-Based Myeloperoxidase Inhibitor for the Treatment of Cardiovascular Diseases
Roger B Ruggeri, Leonard Buckbinder, Scott W Bagley, et al.
Journal of Medicinal Chemistry
|
November 2, 2022
Discovery of Ervogastat (PF-06865571): A Potent and Selective Inhibitor of Diacylglycerol Acyltransferase 2 for the Treatment of Non-alcoholic Steatohepatitis
Kentaro Futatsugi, Shawn Cabral, Daniel W Kung, et al.
Journal of Medicinal Chemistry
|
September 9, 2015
Discovery and Optimization of Imidazopyridine-Based Inhibitors of Diacylglycerol Acyltransferase 2 (DGAT2)
Kentaro Futatsugi, Daniel W Kung, Suvi T M Orr, et al.
Page
of 12
Search research articles
Search
Showing results (101-110 of 116) with videos related to
Sort By:
Page
of 12
The American Journal of Pathology
|
November 15, 2011
BACE2 expression increases in human neurodegenerative disease
Christopher J Holler, Robin L Webb, Ashley L Laux, et al.
ACS Medicinal Chemistry Letters
|
February 20, 2018
Discovery and in Vitro Optimization of 3-Sulfamoylbenzamides as ROMK Inhibitors
Matthew F Sammons, Sujay V Kharade, Kevin J Filipski, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 9, 2023
Discovery of PFI-6, a small-molecule chemical probe for the YEATS domain of MLLT1 and MLLT3
Brigitt Raux, Karly A Buchan, James Bennett, et al.
ACS Medicinal Chemistry Letters
|
December 1, 2015
Discovery of an in Vivo Tool to Establish Proof-of-Concept for MAP4K4-Based Antidiabetic Treatment
Mark Ammirati, Scott W Bagley, Samit K Bhattacharya, et al.
RSC Medicinal Chemistry
|
March 22, 2024
Chemical tools for the Gid4 subunit of the human E3 ligase C-terminal to LisH (CTLH) degradation complex
Aliakbar Khalili Yazdi, Sumera Perveen, Cheng Dong, et al.
Medchemcomm
|
August 16, 2018
Small structural changes of the imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitors produce an improved safety profile
K Futatsugi, K Huard, D W Kung, et al.
Journal of Medicinal Chemistry
|
September 10, 2020
Discovery of PF-06835919: A Potent Inhibitor of Ketohexokinase (KHK) for the Treatment of Metabolic Disorders Driven by the Overconsumption of Fructose
Kentaro Futatsugi, Aaron C Smith, Meihua Tu, et al.
Journal of Medicinal Chemistry
|
October 29, 2015
Discovery of 2-(6-(5-Chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide (PF-06282999): A Highly Selective Mechanism-Based Myeloperoxidase Inhibitor for the Treatment of Cardiovascular Diseases
Roger B Ruggeri, Leonard Buckbinder, Scott W Bagley, et al.
Journal of Medicinal Chemistry
|
November 2, 2022
Discovery of Ervogastat (PF-06865571): A Potent and Selective Inhibitor of Diacylglycerol Acyltransferase 2 for the Treatment of Non-alcoholic Steatohepatitis
Kentaro Futatsugi, Shawn Cabral, Daniel W Kung, et al.
Journal of Medicinal Chemistry
|
September 9, 2015
Discovery and Optimization of Imidazopyridine-Based Inhibitors of Diacylglycerol Acyltransferase 2 (DGAT2)
Kentaro Futatsugi, Daniel W Kung, Suvi T M Orr, et al.
Page
of 12