Showing results (21-30 of 43) with videos related to
Sort By:
Pageof 5
Journal of Medicinal Chemistry|May 29, 2013
Development and binding mode assessment of N-[4-[2-propyn-1-yl[(6S)-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-3H-cyclopenta[g]quinazolin-6-yl]amino]benzoyl]-l-γ-glutamyl-D-glutamic acid (BGC 945), a novel thymidylate synthase inhibitor that targets tumor cellsAnna Tochowicz, Sean Dalziel, Oliv Eidam, et al.Biochemistry|April 8, 2021
Caught in Action: X-ray Structure of Thymidylate Synthase with Noncovalent Intermediate AnalogSvetlana A Kholodar, Janet S Finer-Moore, Katarzyna Świderek, et al.Science (New York, N.Y.)|January 23, 1987
Atomic structure of thymidylate synthase: target for rational drug designL W Hardy, J S Finer-Moore, W R Montfort, et al.Proceedings of the National Academy of Sciences of the United States of America|July 5, 2014
Structure of a new DNA-binding domain which regulates pathogenesis in a wide variety of fungiMatthew B Lohse, Oren S Rosenberg, Jeffery S Cox, et al.Journal of Molecular Biology|November 25, 1998
Inactivity of N229A thymidylate synthase due to water-mediated effects: isolating a late stage in methyl transferC L Reyes, C R Sage, E E Rutenber, et al.Journal of Molecular Biology|March 26, 1998
Contributions of orientation and hydrogen bonding to catalysis in Asn229 mutants of thymidylate synthaseJ S Finer-Moore, L Liu, D L Birdsall, et al.Biochemistry|April 23, 1996
Partitioning roles of side chains in affinity, orientation, and catalysis with structures for mutant complexes: asparagine-229 in thymidylate synthaseJ S Finer-Moore, L Liu, C E Schafmeister, et al.Acta Crystallographica. Section D, Biological Crystallography|October 6, 2005
The structure of Cryptococcus neoformans thymidylate synthase suggests strategies for using target dynamics for species-specific inhibitionJanet S Finer-Moore, Amy C Anderson, Robert H O'Neil, et al.Proceedings of the National Academy of Sciences of the United States of America|July 29, 2011
EspR, a key regulator of Mycobacterium tuberculosis virulence, adopts a unique dimeric structure among helix-turn-helix proteinsOren S Rosenberg, Cole Dovey, Michael Tempesta, et al.Proteins|January 1, 1990
Plastic adaptation toward mutations in proteins: structural comparison of thymidylate synthasesK M Perry, E B Fauman, J S Finer-Moore, et al.Pageof 5