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Journal of Medicinal Chemistry|December 2, 2025
Selective CDK6 Degradation via the KLHDC2 E3 Ubiquitin LigaseEunhye Jeon, Younghoon Kim, Hyunwoo Ahn, et al.Integrative Cancer Therapies|August 20, 2021
Associations of Physical Activity and Exercise with Health-related Outcomes in Patients with Melanoma During and After Treatment: A Systematic ReviewBrendan J Crosby, Pedro Lopez, Daniel A Galvão, et al.Journal of Medicinal Chemistry|September 24, 2010
Discovery of 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one as a highly potent, selective mammalian target of rapamycin (mTOR) inhibitor for the treatment of cancerQingsong Liu, Jae Won Chang, Jinhua Wang, et al.Proceedings of the National Academy of Sciences of the United States of America|August 5, 1997
CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primatesA D Kirk, D M Harlan, N N Armstrong, et al.Journal of Immunology (Baltimore, Md. : 1950)|October 1, 1993
Characterization of CTLA-4 structure and expression on human T cellsT Lindsten, K P Lee, E S Harris, et al.Bioorganic & Medicinal Chemistry Letters|August 3, 2020
Discovery of a series of benzopyrimidodiazepinone TNK2 inhibitors via scaffold morphingZhengnian Li, Chelsea E Powell, Brian J Groendyke, et al.Bioorganic & Medicinal Chemistry Letters|May 27, 2019
Quinoline and thiazolopyridine allosteric inhibitors of MALT1David A Scott, John M Hatcher, Hongyan Liu, et al.Proceedings of the National Academy of Sciences of the United States of America|April 12, 1994
Mice expressing both B7-1 and viral glycoprotein on pancreatic beta cells along with glycoprotein-specific transgenic T cells develop diabetes due to a breakdown of T-lymphocyte unresponsivenessD M Harlan, H Hengartner, M L Huang, et al.Chemistry & Biology|March 27, 2010
A structure-guided approach to creating covalent FGFR inhibitorsWenjun Zhou, Wooyoung Hur, Ultan McDermott, et al.Methods in Molecular Biology (Clifton, N.J.)|November 30, 2011
Development of ATP-competitive mTOR inhibitorsQingsong Liu, Seong A Kang, Carson C Thoreen, et al.Pageof 156