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Journal of Medicinal Chemistry|January 14, 2022
Novel Macrocyclic Peptidomimetics Targeting the Polo-Box Domain of Polo-Like Kinase 1SeongShick Ryu, Jung-Eun Park, Young Jin Ham, et al.Cancer Immunology Research|September 23, 2018
A High-Throughput Immune-Oncology Screen Identifies EGFR Inhibitors as Potent Enhancers of Antigen-Specific Cytotoxic T-lymphocyte Tumor Cell KillingPatrick H Lizotte, Ruey-Long Hong, Troy A Luster, et al.Cell Reports. Medicine|February 1, 2021
Targeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identityHadley E Sheppard, Alessandra Dall'Agnese, Woojun D Park, et al.Cell Chemical Biology|August 8, 2017
Potent and Selective Covalent Quinazoline Inhibitors of KRAS G12CMei Zeng, Jia Lu, Lianbo Li, et al.Cell Chemical Biology|November 14, 2017
A Chemoproteomic Approach to Query the Degradable Kinome Using a Multi-kinase DegraderHai-Tsang Huang, Dennis Dobrovolsky, Joshiawa Paulk, et al.Nature Communications|May 1, 2026
Activating p53Y220C with a mutant-specific small moleculeXijun Zhu, Woong Sub Byun, Dominika Ewa Pieńkowska, et al.Journal of Medicinal Chemistry|January 12, 2024
Discovery of Potent Antimalarial Type II Kinase Inhibitors with Selectivity over Human KinasesLushun Wang, Monica J Bohmer, Jinhua Wang, et al.Cell Stem Cell|August 5, 2014
Systematic identification of culture conditions for induction and maintenance of naive human pluripotencyThorold W Theunissen, Benjamin E Powell, Haoyi Wang, et al.Cancer Discovery|May 17, 2019
Single and Dual Targeting of Mutant EGFR with an Allosteric InhibitorCiric To, Jaebong Jang, Ting Chen, et al.Nature Communications|April 17, 2019
CDK12 loss in cancer cells affects DNA damage response genes through premature cleavage and polyadenylationMalgorzata Krajewska, Ruben Dries, Andrew V Grassetti, et al.Pageof 156