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Journal of Medicinal Chemistry|April 4, 2014
Siderophore receptor-mediated uptake of lactivicin analogues in gram-negative bacteriaJeremy Starr, Matthew F Brown, Lisa Aschenbrenner, et al.Journal of Medicinal Chemistry|October 26, 2012
Identification of a chemical probe for bromo and extra C-terminal bromodomain inhibition through optimization of a fragment-derived hitPaul V Fish, Panagis Filippakopoulos, Gerwyn Bish, et al.Science Advances|December 25, 2015
Selective targeting of the BRG/PB1 bromodomains impairs embryonic and trophoblast stem cell maintenanceOleg Fedorov, Josefina Castex, Cynthia Tallant, et al.Journal of Medicinal Chemistry|February 17, 2025
Conformational Role of Methyl in the Potency of Cyclohexane-Substituted Squaramide CCR6 AntagonistsBrian S Gerstenberger, Ray Unwalla, Kathleen A Farley, et al.Bioorganic & Medicinal Chemistry|April 8, 2020
Design and optimization of a series of 4-(3-azabicyclo[3.1.0]hexan-3-yl)pyrimidin-2-amines: Dual inhibitors of TYK2 and JAK1Andrew Fensome, Catherine M Ambler, Eric Arnold, et al.Journal of Medicinal Chemistry|August 14, 2020
Discovery of Tyrosine Kinase 2 (TYK2) Inhibitor (PF-06826647) for the Treatment of Autoimmune DiseasesBrian S Gerstenberger, Catherine Ambler, Eric P Arnold, et al.Journal of Medicinal Chemistry|April 27, 2016
Identification of a Chemical Probe for Family VIII Bromodomains through Optimization of a Fragment HitBrian S Gerstenberger, John D Trzupek, Cynthia Tallant, et al.ACS Chemical Biology|August 30, 2017
Selective Targeting of Bromodomains of the Bromodomain-PHD Fingers Family Impairs Osteoclast DifferentiationJulia C Meier, Cynthia Tallant, Oleg Fedorov, et al.Journal of Medicinal Chemistry|August 17, 2018
Dual Inhibition of TYK2 and JAK1 for the Treatment of Autoimmune Diseases: Discovery of (( S)-2,2-Difluorocyclopropyl)((1 R,5 S)-3-(2-((1-methyl-1 H-pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone (PF-06700841)Andrew Fensome, Catherine M Ambler, Eric Arnold, et al.Nature Communications|August 31, 2024
Structural basis for CCR6 modulation by allosteric antagonistsDavid Jonathan Wasilko, Brian S Gerstenberger, Kathleen A Farley, et al.Pageof 3