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Investigational New Drugs|September 29, 2018
E6201, an intravenous MEK1 inhibitor, achieves an exceptional response in BRAF V600E-mutated metastatic malignant melanoma with brain metastasesHani M Babiker, Sara A Byron, William P D Hendricks, et al.
BMC Medical Genomics|January 7, 2021
Association between triglycerides, known risk SNVs and conserved rare variation in SLC25A40 in a multi-ancestry cohortElisabeth A Rosenthal, David R Crosslin, Adam S Gordon, et al.
Cell|May 7, 2022
Recurrent inversion polymorphisms in humans associate with genetic instability and genomic disordersDavid Porubsky, Wolfram Höps, Hufsah Ashraf, et al.
JAMA Oncology|September 28, 2023
Anti-TIGIT Antibody Tiragolumab Alone or With Atezolizumab in Patients With Advanced Solid Tumors: A Phase 1a/1b Nonrandomized Controlled TrialTae Won Kim, Philippe L Bedard, Patricia LoRusso, et al.
The Lancet. Oncology|July 19, 2012
Activity of the oral MEK inhibitor trametinib in patients with advanced melanoma: a phase 1 dose-escalation trialGerald S Falchook, Karl D Lewis, Jeffrey R Infante, et al.
JAMA Network Open|June 26, 2024
Concordance With Screening and Treatment Guidelines for Chronic Kidney Disease in Type 2 DiabetesDaniel Edmonston, Elizabeth Lydon, Hillary Mulder, et al.
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology|September 17, 2014
Cabozantinib in chemotherapy-pretreated metastatic castration-resistant prostate cancer: results of a phase II nonrandomized expansion studyMatthew R Smith, Christopher J Sweeney, Paul G Corn, et al.
Cancer Discovery|February 13, 2018
Combined BRAF, EGFR, and MEK Inhibition in Patients with <i>BRAF</i><sup>V600E</sup>-Mutant Colorectal CancerRyan B Corcoran, Thierry André, Chloe E Atreya, et al.
Nature Communications|December 5, 2023
Leukemia-intrinsic determinants of CAR-T response revealed by iterative in vivo genome-wide CRISPR screeningAzucena Ramos, Catherine E Koch, Yunpeng Liu-Lupo, et al.
Human Molecular Genetics|November 28, 2013
Quantifying rare, deleterious variation in 12 human cytochrome P450 drug-metabolism genes in a large-scale exome datasetAdam S Gordon, Holly K Tabor, Andrew D Johnson, et al.
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