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Protein Expression and Purification|January 12, 1999
Prepro-leaders lacking N-linked glycosylation for secretory expression in the yeast Saccharomyces cerevisiaeT Kjeldsen, M Hach, P Balschmidt, et al.
The Biochemical Journal|December 15, 1995
Albumin binding of insulins acylated with fatty acids: characterization of the ligand-protein interaction and correlation between binding affinity and timing of the insulin effect in vivoP Kurtzhals, S Havelund, I Jonassen, et al.
Protein Expression and Purification|April 1, 1997
Synthetic leaders with potential BiP binding mediate high-yield secretion of correctly folded insulin precursors from Saccharomyces cerevisiaeT Kjeldsen, A F Pettersson, M Hach, et al.
Biochimica Et Biophysica Acta|September 27, 2000
Conformational correlation and coupled motion between residue A21 and B25 side chain observed in crystal structures of insulin mutants at position A21Z H Zeng, Y S Liu, L Jin, et al.
Protein Expression and Purification|July 24, 1998
Secretory expression of human albumin domains in Saccharomyces cerevisiae and their binding of myristic acid and an acylated insulin analogueT Kjeldsen, A F Pettersson, L Drube, et al.
Diabetologia|December 1, 1994
The potential immunogenicity of human insulin and insulin analogues evaluated in a transgenic mouse modelJ L Ottesen, P Nilsson, J Jami, et al.
Biochemistry|October 12, 1993
Engineering stability of the insulin monomer fold with application to structure-activity relationshipsN C Kaarsholm, K Norris, R J Jørgensen, et al.
The Journal of Biological Chemistry|May 16, 1997
Alanine scanning mutagenesis of insulinC Kristensen, T Kjeldsen, F C Wiberg, et al.
Nature|June 16, 1988
Monomeric insulins obtained by protein engineering and their medical implicationsJ Brange, U Ribel, J F Hansen, et al.
Diabetologia|March 1, 1996
Soluble, fatty acid acylated insulins bind to albumin and show protracted action in pigsJ Markussen, S Havelund, P Kurtzhals, et al.
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