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Journal of Medicinal Chemistry|March 9, 2011
The discovery of phthalazinone-based human H1 and H3 single-ligand antagonists suitable for intranasal administration for the treatment of allergic rhinitisPanayiotis A Procopiou, Christopher Browning, Jennifer M Buckley, et al.Bioorganic & Medicinal Chemistry Letters|March 25, 2017
The discovery of potent and selective kynurenine 3-monooxygenase inhibitors for the treatment of acute pancreatitisJohn Liddle, Benjamin Beaufils, Margaret Binnie, et al.Journal of Medicinal Chemistry|December 7, 2007
4-acyl-1-(4-aminoalkoxyphenyl)-2-ketopiperazines as a novel class of non-brain-penetrant histamine H3 receptor antagonistsPanayiotis A Procopiou, Rachael A Ancliff, Mark J Bamford, et al.Bioorganic & Medicinal Chemistry Letters|July 18, 2012
4-Phenyl-7-azaindoles as potent, selective and bioavailable IKK2 inhibitors demonstrating good in vivo efficacyJohn Liddle, Paul Bamborough, Michael D Barker, et al.Journal of Medicinal Chemistry|August 16, 2011
Discovery of a brain-penetrant S1P₃-sparing direct agonist of the S1P₁ and S1P₅ receptors efficacious at low oral doseEmmanuel H Demont, Sandra Arpino, Rino A Bit, et al.Neuropsychologia|November 13, 2023
Guidelines for reporting action simulation studies (GRASS): Proposals to improve reporting of research in motor imagery and action observationMarcos Moreno-Verdú, Gautier Hamoline, Elise E Van Caenegem, et al.Proceedings of the National Academy of Sciences of the United States of America|September 15, 1999
Orexin A activates locus coeruleus cell firing and increases arousal in the ratJ J Hagan, R A Leslie, S Patel, et al.Journal of Medicinal Chemistry|May 14, 2010
Synthesis and structure-activity relationships of long-acting beta2 adrenergic receptor agonists incorporating metabolic inactivation: an antedrug approachPanayiotis A Procopiou, Victoria J Barrett, Nicola J Bevan, et al.Bioorganic & Medicinal Chemistry Letters|August 7, 2009
Quinolines as a novel structural class of potent and selective PDE4 inhibitors. Optimisation for inhaled administrationMichael D Woodrow, Stuart P Ballantine, Michael D Barker, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of a Selective S1P1 Receptor Agonist Efficacious at Low Oral Dose and Devoid of Effects on Heart RateEmmanuel H Demont, Benjamin I Andrews, Rino A Bit, et al.Pageof 68