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Cell|August 8, 1997
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutationS W Davies, M Turmaine, B A Cozens, et al.
The Journal of Clinical Investigation|July 26, 2011
Altered chromatin architecture underlies progressive impairment of the heat shock response in mouse models of Huntington diseaseJohn Labbadia, Helen Cunliffe, Andreas Weiss, et al.
Human Molecular Genetics|April 15, 2006
Progressive alterations in the hypothalamic-pituitary-adrenal axis in the R6/2 transgenic mouse model of Huntington's diseaseMaria Björkqvist, Asa Petersén, Karl Bacos, et al.
Human Molecular Genetics|October 26, 2018
FAN1 modifies Huntington's disease progression by stabilizing the expanded HTT CAG repeatRobert Goold, Michael Flower, Davina Hensman Moss, et al.
Proceedings of the National Academy of Sciences of the United States of America|May 24, 2000
The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcriptionJ S Steffan, A Kazantsev, O Spasic-Boskovic, et al.
Plos One|December 27, 2022
Reduction in PA28αβ activation in HD mouse brain correlates to increased mHTT aggregation in cell modelsKarlijne W Geijtenbeek, Jolien Janzen, Aleksandra E Bury, et al.
Brain Communications|February 19, 2021
Development of novel bioassays to detect soluble and aggregated Huntingtin proteins on three technology platformsChristian Landles, Rebecca E Milton, Alexandre Jean, et al.
Nucleic Acids Research|December 24, 1998
The integral divalent cation within the intermolecular purine*purine. pyrimidine structure: a variable determinant of the potential for and characteristics of the triple helical associationS W Blume, J Lebowitz, W Zacharias, et al.
Brain : a Journal of Neurology|August 18, 2024
Exon 1-targeting miRNA reduces the pathogenic exon 1 HTT protein in Huntington's disease modelsMarina Sogorb-Gonzalez, Christian Landles, Nicholas S Caron, et al.
Neurobiology of Disease|May 16, 2006
Elevated brain 3-hydroxykynurenine and quinolinate levels in Huntington disease micePaolo Guidetti, Gillian P Bates, Rona K Graham, et al.
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