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Plos One|September 18, 2012
Fragments of HdhQ150 mutant huntingtin form a soluble oligomer pool that declines with aggregate deposition upon agingDavid Marcellin, Dorothee Abramowski, Douglas Young, et al.Brain : a Journal of Neurology|February 22, 2024
A CAG repeat threshold for therapeutics targeting somatic instability in Huntington's diseaseSarah G Aldous, Edward J Smith, Christian Landles, et al.Brain Communications|September 21, 2020
Subcellular Localization And Formation Of Huntingtin Aggregates Correlates With Symptom Onset And Progression In A Huntington'S Disease ModelChristian Landles, Rebecca E Milton, Nadira Ali, et al.Proceedings of the National Academy of Sciences of the United States of America|February 11, 2003
Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's diseaseEmma Hockly, Victoria M Richon, Benjamin Woodman, et al.Human Molecular Genetics|September 27, 2005
Contribution of nuclear and extranuclear polyQ to neurological phenotypes in mouse models of Huntington's diseaseCaroline L Benn, Christian Landles, He Li, et al.FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|April 25, 2020
Expression of mutant exon 1 huntingtin fragments in human neural stem cells and neurons causes inclusion formation and mitochondrial dysfunctionRhia Ghosh, Alison Wood-Kaczmar, Lucianne Dobson, et al.Plos One|September 14, 2012
Oral administration of the pimelic diphenylamide HDAC inhibitor HDACi 4b is unsuitable for chronic inhibition of HDAC activity in the CNS in vivoMaria Beconi, Omar Aziz, Kim Matthews, et al.Neurobiology of Disease|October 9, 2007
Increased metabolism in the R6/2 mouse model of Huntington's diseaseJorien M M van der Burg, Karl Bacos, Nigel I Wood, et al.Proceedings of the National Academy of Sciences of the United States of America|January 12, 2005
A potent small molecule inhibits polyglutamine aggregation in Huntington's disease neurons and suppresses neurodegeneration in vivoXiaoqian Zhang, Donna L Smith, Anatoli B Meriin, et al.Disease Models & Mechanisms|May 26, 2026
Molecular features of a Huntington's disease knock-in minipigAnastasiia Kolesnikova, Kirupa Sathasivam, Solaleh Khoramian Tusi, et al.Pageof 38