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Plos One|September 18, 2012
Fragments of HdhQ150 mutant huntingtin form a soluble oligomer pool that declines with aggregate deposition upon agingDavid Marcellin, Dorothee Abramowski, Douglas Young, et al.
Brain : a Journal of Neurology|February 22, 2024
A CAG repeat threshold for therapeutics targeting somatic instability in Huntington's diseaseSarah G Aldous, Edward J Smith, Christian Landles, et al.
Brain Communications|September 21, 2020
Subcellular Localization And Formation Of Huntingtin Aggregates Correlates With Symptom Onset And Progression In A Huntington'S Disease ModelChristian Landles, Rebecca E Milton, Nadira Ali, et al.
Proceedings of the National Academy of Sciences of the United States of America|February 11, 2003
Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's diseaseEmma Hockly, Victoria M Richon, Benjamin Woodman, et al.
Human Molecular Genetics|September 27, 2005
Contribution of nuclear and extranuclear polyQ to neurological phenotypes in mouse models of Huntington's diseaseCaroline L Benn, Christian Landles, He Li, et al.
FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|April 25, 2020
Expression of mutant exon 1 huntingtin fragments in human neural stem cells and neurons causes inclusion formation and mitochondrial dysfunctionRhia Ghosh, Alison Wood-Kaczmar, Lucianne Dobson, et al.
Neurobiology of Disease|October 9, 2007
Increased metabolism in the R6/2 mouse model of Huntington's diseaseJorien M M van der Burg, Karl Bacos, Nigel I Wood, et al.
Proceedings of the National Academy of Sciences of the United States of America|January 12, 2005
A potent small molecule inhibits polyglutamine aggregation in Huntington's disease neurons and suppresses neurodegeneration in vivoXiaoqian Zhang, Donna L Smith, Anatoli B Meriin, et al.
Disease Models & Mechanisms|May 26, 2026
Molecular features of a Huntington's disease knock-in minipigAnastasiia Kolesnikova, Kirupa Sathasivam, Solaleh Khoramian Tusi, et al.
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