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Science Signaling
|
July 18, 2019
Application of a MYC degradation screen identifies sensitivity to CDK9 inhibitors in KRAS-mutant pancreatic cancer
Devon R Blake, Angelina V Vaseva, Richard G Hodge, et al.
ACS Chemical Biology
|
April 26, 2019
Mitochondrial Protease ClpP is a Target for the Anticancer Compounds ONC201 and Related Analogues
Paul R Graves, Lucas J Aponte-Collazo, Emily M J Fennell, et al.
SLAS Discovery : Advancing Life Sciences R & D
|
May 10, 2018
Application of Integrated Drug Screening/Kinome Analysis to Identify Inhibitors of Gemcitabine-Resistant Pancreatic Cancer Cell Growth
Linas J Krulikas, Ian M McDonald, Benjamin Lee, et al.
The Journal of Biological Chemistry
|
October 24, 2021
The KRAS-regulated kinome identifies WEE1 and ERK coinhibition as a potential therapeutic strategy in KRAS-mutant pancreatic cancer
J Nathaniel Diehl, Jennifer E Klomp, Kayla R Snare, et al.
Journal of Proteome Research
|
August 27, 2023
Investigation of the Host Kinome Response to Coronavirus Infection Reveals PI3K/mTOR Inhibitors as Betacoronavirus Antivirals
Ethan J Fritch, Angie L Mordant, Thomas S K Gilbert, et al.
Journal of the American Chemical Society
|
September 10, 2019
Data-Driven Construction of Antitumor Agents with Controlled Polypharmacology
Chenxiao Da, Dehui Zhang, Michael Stashko, et al.
Cancer Cell
|
November 14, 2018
KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism
Angelina V Vaseva, Devon R Blake, Thomas S K Gilbert, et al.
Cell Reports
|
June 20, 2020
Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers
Irem Ozkan-Dagliyan, J Nathaniel Diehl, Samuel D George, et al.
Cell Reports
|
June 30, 2021
Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition
Andrew M Waters, Tala O Khatib, Bjoern Papke, et al.
Plos One
|
July 15, 2021
Brigatinib causes tumor shrinkage in both NF2-deficient meningioma and schwannoma through inhibition of multiple tyrosine kinases but not ALK
Long-Sheng Chang, Janet L Oblinger, Abbi E Smith, et al.
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Showing results (11-20 of 20) with videos related to
Sort By:
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This site can display upto 20 results.
Science Signaling
|
July 18, 2019
Application of a MYC degradation screen identifies sensitivity to CDK9 inhibitors in KRAS-mutant pancreatic cancer
Devon R Blake, Angelina V Vaseva, Richard G Hodge, et al.
ACS Chemical Biology
|
April 26, 2019
Mitochondrial Protease ClpP is a Target for the Anticancer Compounds ONC201 and Related Analogues
Paul R Graves, Lucas J Aponte-Collazo, Emily M J Fennell, et al.
SLAS Discovery : Advancing Life Sciences R & D
|
May 10, 2018
Application of Integrated Drug Screening/Kinome Analysis to Identify Inhibitors of Gemcitabine-Resistant Pancreatic Cancer Cell Growth
Linas J Krulikas, Ian M McDonald, Benjamin Lee, et al.
The Journal of Biological Chemistry
|
October 24, 2021
The KRAS-regulated kinome identifies WEE1 and ERK coinhibition as a potential therapeutic strategy in KRAS-mutant pancreatic cancer
J Nathaniel Diehl, Jennifer E Klomp, Kayla R Snare, et al.
Journal of Proteome Research
|
August 27, 2023
Investigation of the Host Kinome Response to Coronavirus Infection Reveals PI3K/mTOR Inhibitors as Betacoronavirus Antivirals
Ethan J Fritch, Angie L Mordant, Thomas S K Gilbert, et al.
Journal of the American Chemical Society
|
September 10, 2019
Data-Driven Construction of Antitumor Agents with Controlled Polypharmacology
Chenxiao Da, Dehui Zhang, Michael Stashko, et al.
Cancer Cell
|
November 14, 2018
KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism
Angelina V Vaseva, Devon R Blake, Thomas S K Gilbert, et al.
Cell Reports
|
June 20, 2020
Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers
Irem Ozkan-Dagliyan, J Nathaniel Diehl, Samuel D George, et al.
Cell Reports
|
June 30, 2021
Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition
Andrew M Waters, Tala O Khatib, Bjoern Papke, et al.
Plos One
|
July 15, 2021
Brigatinib causes tumor shrinkage in both NF2-deficient meningioma and schwannoma through inhibition of multiple tyrosine kinases but not ALK
Long-Sheng Chang, Janet L Oblinger, Abbi E Smith, et al.
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of 2