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Expert Opinion on Drug Discovery
|
July 26, 2012
De novo design: balancing novelty and confined chemical space
Peter S Kutchukian, Eugene I Shakhnovich
Journal of Chemical Information and Modeling
|
June 17, 2009
FOG: Fragment Optimized Growth algorithm for the de novo generation of molecules occupying druglike chemical space
Peter S Kutchukian, David Lou, Eugene I Shakhnovich
Organic Letters
|
June 10, 2010
Introduction of all-hydrocarbon i,i+3 staples into alpha-helices via ring-closing olefin metathesis
Young-Woo Kim, Peter S Kutchukian, Gregory L Verdine
Methods in Molecular Biology (Clifton, N.J.)
|
February 25, 2015
Fragment library design: using cheminformatics and expert chemists to fill gaps in existing fragment libraries
Peter S Kutchukian, Sung-Sau So, Christian Fischer, et al.
Journal of the American Chemical Society
|
April 2, 2009
All-atom model for stabilization of alpha-helical structure in peptides by hydrocarbon staples
Peter S Kutchukian, Jae Shick Yang, Gregory L Verdine, et al.
Plos Computational Biology
|
February 10, 2017
Representing high throughput expression profiles via perturbation barcodes reveals compound targets
Tracey M Filzen, Peter S Kutchukian, Jeffrey D Hermes, et al.
Journal of Cheminformatics
|
March 22, 2024
Pocket Crafter: a 3D generative modeling based workflow for the rapid generation of hit molecules in drug discovery
Lingling Shen, Jian Fang, Lulu Liu, et al.
The Journal of Biological Chemistry
|
May 25, 2001
Reaction of superoxide and nitric oxide with peroxynitrite. Implications for peroxynitrite-mediated oxidation reactions in vivo
D Jourd'heuil, F L Jourd'heuil, P S Kutchukian, et al.
The Journal of Biological Chemistry
|
April 19, 2012
Enforced presentation of an extrahelical guanine to the lesion recognition pocket of human 8-oxoguanine glycosylase, hOGG1
Charisse M Crenshaw, Kwangho Nam, Kimberly Oo, et al.
Journal of the American Chemical Society
|
December 14, 2011
Structure of the stapled p53 peptide bound to Mdm2
Sohee Baek, Peter S Kutchukian, Gregory L Verdine, et al.
Page
of 3
Search research articles
Search
Showing results (1-10 of 30) with videos related to
Sort By:
Page
of 3
Expert Opinion on Drug Discovery
|
July 26, 2012
De novo design: balancing novelty and confined chemical space
Peter S Kutchukian, Eugene I Shakhnovich
Journal of Chemical Information and Modeling
|
June 17, 2009
FOG: Fragment Optimized Growth algorithm for the de novo generation of molecules occupying druglike chemical space
Peter S Kutchukian, David Lou, Eugene I Shakhnovich
Organic Letters
|
June 10, 2010
Introduction of all-hydrocarbon i,i+3 staples into alpha-helices via ring-closing olefin metathesis
Young-Woo Kim, Peter S Kutchukian, Gregory L Verdine
Methods in Molecular Biology (Clifton, N.J.)
|
February 25, 2015
Fragment library design: using cheminformatics and expert chemists to fill gaps in existing fragment libraries
Peter S Kutchukian, Sung-Sau So, Christian Fischer, et al.
Journal of the American Chemical Society
|
April 2, 2009
All-atom model for stabilization of alpha-helical structure in peptides by hydrocarbon staples
Peter S Kutchukian, Jae Shick Yang, Gregory L Verdine, et al.
Plos Computational Biology
|
February 10, 2017
Representing high throughput expression profiles via perturbation barcodes reveals compound targets
Tracey M Filzen, Peter S Kutchukian, Jeffrey D Hermes, et al.
Journal of Cheminformatics
|
March 22, 2024
Pocket Crafter: a 3D generative modeling based workflow for the rapid generation of hit molecules in drug discovery
Lingling Shen, Jian Fang, Lulu Liu, et al.
The Journal of Biological Chemistry
|
May 25, 2001
Reaction of superoxide and nitric oxide with peroxynitrite. Implications for peroxynitrite-mediated oxidation reactions in vivo
D Jourd'heuil, F L Jourd'heuil, P S Kutchukian, et al.
The Journal of Biological Chemistry
|
April 19, 2012
Enforced presentation of an extrahelical guanine to the lesion recognition pocket of human 8-oxoguanine glycosylase, hOGG1
Charisse M Crenshaw, Kwangho Nam, Kimberly Oo, et al.
Journal of the American Chemical Society
|
December 14, 2011
Structure of the stapled p53 peptide bound to Mdm2
Sohee Baek, Peter S Kutchukian, Gregory L Verdine, et al.
Page
of 3