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Bone
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September 12, 2006
A highly potent inhibitor of cathepsin K (relacatib) reduces biomarkers of bone resorption both in vitro and in an acute model of elevated bone turnover in vivo in monkeys
S Kumar, L Dare, J A Vasko-Moser, et al.
Bone
|
May 9, 2002
A potent small molecule, nonpeptide inhibitor of cathepsin K (SB 331750) prevents bone matrix resorption in the ovariectomized rat
Michael W Lark, G B Stroup, I E James, et al.
The Journal of Biological Chemistry
|
June 8, 1999
Identification and cloning of a connective tissue growth factor-like cDNA from human osteoblasts encoding a novel regulator of osteoblast functions
S Kumar, A T Hand, J R Connor, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
October 19, 1999
Design and characterization of orally active Arg-Gly-Asp peptidomimetic vitronectin receptor antagonist SB 265123 for prevention of bone loss in osteoporosis
M W Lark, G B Stroup, S M Hwang, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 5, 1999
Benzimidazole derivatives as arginine mimetics in 1,4-benzodiazepine nonpeptide vitronectin receptor (alpha v beta 3) antagonists
R M Keenan, W H Miller, M A Lago, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 5, 1999
Discovery of an imidazopyridine-containing 1,4-benzodiazepine nonpeptide vitronectin receptor (alpha v beta 3) antagonist with efficacy in a restenosis model
R M Keenan, M A Lago, W H Miller, et al.
Journal of Medicinal Chemistry
|
March 3, 1999
Conformational preferences in a benzodiazepine series of potent nonpeptide fibrinogen receptor antagonists
R M Keenan, J F Callahan, J M Samanen, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 16, 1999
Orally bioavailable nonpeptide vitronectin receptor antagonists with efficacy in an osteoporosis model
W H Miller, W E Bondinell, R D Cousins, et al.
Journal of Medicinal Chemistry
|
December 6, 1996
Potent, selective, orally active 3-oxo-1,4-benzodiazepine GPIIb/IIIa integrin antagonists
J M Samanen, F E Ali, L S Barton, et al.
Journal of Medicinal Chemistry
|
January 14, 2000
Discovery of orally active nonpeptide vitronectin receptor antagonists based on a 2-benzazepine Gly-Asp mimetic
W H Miller, D P Alberts, P K Bhatnagar, et al.
Page
of 13
Search research articles
Search
Showing results (111-120 of 122) with videos related to
Sort By:
Page
of 13
Bone
|
September 12, 2006
A highly potent inhibitor of cathepsin K (relacatib) reduces biomarkers of bone resorption both in vitro and in an acute model of elevated bone turnover in vivo in monkeys
S Kumar, L Dare, J A Vasko-Moser, et al.
Bone
|
May 9, 2002
A potent small molecule, nonpeptide inhibitor of cathepsin K (SB 331750) prevents bone matrix resorption in the ovariectomized rat
Michael W Lark, G B Stroup, I E James, et al.
The Journal of Biological Chemistry
|
June 8, 1999
Identification and cloning of a connective tissue growth factor-like cDNA from human osteoblasts encoding a novel regulator of osteoblast functions
S Kumar, A T Hand, J R Connor, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
October 19, 1999
Design and characterization of orally active Arg-Gly-Asp peptidomimetic vitronectin receptor antagonist SB 265123 for prevention of bone loss in osteoporosis
M W Lark, G B Stroup, S M Hwang, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 5, 1999
Benzimidazole derivatives as arginine mimetics in 1,4-benzodiazepine nonpeptide vitronectin receptor (alpha v beta 3) antagonists
R M Keenan, W H Miller, M A Lago, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 5, 1999
Discovery of an imidazopyridine-containing 1,4-benzodiazepine nonpeptide vitronectin receptor (alpha v beta 3) antagonist with efficacy in a restenosis model
R M Keenan, M A Lago, W H Miller, et al.
Journal of Medicinal Chemistry
|
March 3, 1999
Conformational preferences in a benzodiazepine series of potent nonpeptide fibrinogen receptor antagonists
R M Keenan, J F Callahan, J M Samanen, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 16, 1999
Orally bioavailable nonpeptide vitronectin receptor antagonists with efficacy in an osteoporosis model
W H Miller, W E Bondinell, R D Cousins, et al.
Journal of Medicinal Chemistry
|
December 6, 1996
Potent, selective, orally active 3-oxo-1,4-benzodiazepine GPIIb/IIIa integrin antagonists
J M Samanen, F E Ali, L S Barton, et al.
Journal of Medicinal Chemistry
|
January 14, 2000
Discovery of orally active nonpeptide vitronectin receptor antagonists based on a 2-benzazepine Gly-Asp mimetic
W H Miller, D P Alberts, P K Bhatnagar, et al.
Page
of 13