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Communications Biology|April 12, 2022
Tyrosine 121 moves revealing a ligandable pocket that couples catalysis to ATP-binding in serine racemaseChloe R Koulouris, Sian E Gardiner, Tessa K Harris, et al.Molecular Cell|April 28, 2009
Structural insights into formation of an active signaling complex between Rac and phospholipase C gamma 2Tom D Bunney, Olaniyi Opaleye, S Mark Roe, et al.Nature Chemistry|March 21, 2013
Synthesis of 19-substituted geldanamycins with altered conformations and their binding to heat shock protein Hsp90Russell R A Kitson, Chuan-Hsin Chang, Rui Xiong, et al.Bioorganic & Medicinal Chemistry Letters|June 16, 2005
The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitorsKwai-Ming J Cheung, Thomas P Matthews, Karen James, et al.Chemistry & Biology|January 1, 2004
GSK-3-selective inhibitors derived from Tyrian purple indirubinsLaurent Meijer, Alexios-Leandros Skaltsounis, Prokopios Magiatis, et al.Molecular Cell|February 18, 2006
Structural and mechanistic insights into ras association domains of phospholipase C epsilonTom D Bunney, Richard Harris, Natalia Lamuño Gandarillas, et al.Elife|March 1, 2021
Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome proteinXiangrong Chen, Yusuf I Ali, Charlotte El Fisher, et al.Journal of Medicinal Chemistry|September 20, 2008
Optimizing natural products by biosynthetic engineering: discovery of nonquinone Hsp90 inhibitorsMing-Qiang Zhang, Sabine Gaisser, Mohammad Nur-E-Alam, et al.Cancer Research|March 3, 2007
In vitro biological characterization of a novel, synthetic diaryl pyrazole resorcinol class of heat shock protein 90 inhibitorsSwee Y Sharp, Kathy Boxall, Martin Rowlands, et al.Science Advances|November 14, 2020
The structure-function relationship of oncogenic LMTK3Angeliki Ditsiou, Chiara Cilibrasi, Nikiana Simigdala, et al.Pageof 7