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Bioorganic & Medicinal Chemistry Letters|February 27, 2019
Discovery and optimization of novel piperazines as potent inhibitors of fatty acid synthase (FASN)Matthew W Martin, David R Lancia, Hongbin Li, et al.Journal of Medicinal Chemistry|September 6, 2011
Design and synthesis of inhaled p38 inhibitors for the treatment of chronic obstructive pulmonary diseaseDavid S Millan, Mark E Bunnage, Jane L Burrows, et al.Journal of Medicinal Chemistry|February 9, 2026
Discovery and Optimization of Orally Bioavailable Heterobifunctional Degraders of KAT2A/B for the Treatment of CancerJames Neef, Kimberly S Straley, Chinmoy Mukherjee, et al.Journal for Immunotherapy of Cancer|January 13, 2026
Mutant calreticulin enables potent and selective CAR-T cell therapy in preclinical models of myeloproliferative neoplasmsCecilia Pesini, Mario Gil-Bellido, Lorena S Millan, et al.Journal of Medicinal Chemistry|July 7, 2017
Discovery of Clinical Candidate 4-[2-(5-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-1,3-thiazol-4-ylbenzenesulfonamide (PF-05089771): Design and Optimization of Diaryl Ether Aryl Sulfonamides as Selective Inhibitors of NaV1.7Nigel A Swain, Dave Batchelor, Serge Beaudoin, et al.Pageof 4