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Diabetes|November 7, 2023
GIPR Agonism Enhances TZD-Induced Insulin Sensitivity in Obese IR MiceEllen C Furber, Karissa Hyatt, Kyla Collins, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Combination of a Beta adrenoceptor modulator and a norepinephrine-serotonin uptake inhibitor for the treatment of obesityCynthia D Jesudason, James E Baker, Robert D Bryant, et al.Cell Metabolism|August 19, 2022
LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of conceptTamer Coskun, Shweta Urva, William C Roell, et al.Diabetes, Obesity & Metabolism|January 9, 2026
GLP-1R biased cAMP agonism maintains glycemic control with reduced malaise and emesis in preclinical mammalian modelsCaitlin Baumer-Harrison, Danya Aldaghma, Alex D White, et al.Science Translational Medicine|December 18, 2024
The pharmacological basis for nonpeptide agonism of the GLP-1 receptor by orforglipronKyle W Sloop, Amy L Cox, David B Wainscott, et al.Cell Metabolism|June 15, 2024
Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptorAjit Regmi, Eitaro Aihara, Michael E Christe, et al.The Journal of Clinical Investigation|May 18, 2021
GIPR agonism mediates weight-independent insulin sensitization by tirzepatide in obese miceRicardo J Samms, Michael E Christe, Kyla Al Collins, et al.Pageof 3