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Journal of Medicinal Chemistry|August 1, 1991
Inhibitors of the protease from human immunodeficiency virus: design and modeling of a compound containing a dihydroxyethylene isostere insert with high binding affinity and effective antiviral activityS Thaisrivongs, A G Tomasselli, J B Moon, et al.Journal of Medicinal Chemistry|September 1, 1995
Structure-based design of novel HIV protease inhibitors: carboxamide-containing 4-hydroxycoumarins and 4-hydroxy-2-pyrones as potent nonpeptidic inhibitorsS Thaisrivongs, K D Watenpaugh, W J Howe, et al.Antimicrobial Agents and Chemotherapy|June 1, 1994
Effects of U-75875, a peptidomimetic inhibitor of retroviral proteases, on simian immunodeficiency virus infection in rhesus monkeysL N Martin, K F Soike, M Murphey-Corb, et al.Journal of Medicinal Chemistry|April 16, 1993
Inhibitors of the protease from human immunodeficiency virus: synthesis, enzyme inhibition, and antiviral activity of a series of compounds containing the dihydroxyethylene transition-state isostereS Thaisrivongs, S R Turner, J W Strohbach, et al.Antimicrobial Agents and Chemotherapy|May 1, 1997
Antiviral activity of the dihydropyrone PNU-140690, a new nonpeptidic human immunodeficiency virus protease inhibitorS M Poppe, D E Slade, K T Chong, et al.Journal of Medicinal Chemistry|June 7, 1996
Structure-based design of novel HIV protease inhibitors: sulfonamide-containing 4-hydroxycoumarins and 4-hydroxy-2-pyrones as potent non-peptidic inhibitorsS Thaisrivongs, M N Janakiraman, K T Chong, et al.Journal of Medicinal Chemistry|August 28, 1998
Tipranavir (PNU-140690): a potent, orally bioavailable nonpeptidic HIV protease inhibitor of the 5,6-dihydro-4-hydroxy-2-pyrone sulfonamide classS R Turner, J W Strohbach, R A Tommasi, et al.Journal of Medicinal Chemistry|November 8, 1996
Structure-based design of HIV protease inhibitors: 5,6-dihydro-4-hydroxy-2-pyrones as effective, nonpeptidic inhibitorsS Thaisrivongs, D L Romero, R A Tommasi, et al.Pageof 3