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The Journal of Physiology|September 16, 2022
Initiation of 3,3-dimethyl-1-butanol at midlife prevents endothelial dysfunction and attenuates in vivo aortic stiffening with ageing in miceAbigail G Casso, Nicholas S VanDongen, Rachel A Gioscia-Ryan, et al.
The Journal of Physiology|October 26, 2020
Lifelong voluntary aerobic exercise prevents age- and Western diet- induced vascular dysfunction, mitochondrial oxidative stress and inflammation in miceRachel A Gioscia-Ryan, Zachary S Clayton, Melanie C Zigler, et al.
Journal of Applied Physiology (Bethesda, Md. : 1985)|August 11, 2022
Suppression of trimethylamine N-oxide with DMB mitigates vascular dysfunction, exercise intolerance, and frailty associated with a Western-style diet in miceVienna E Brunt, Nathan T Greenberg, Zachary J Sapinsley, et al.
American Journal of Physiology. Heart and Circulatory Physiology|June 11, 2021
Apigenin restores endothelial function by ameliorating oxidative stress, reverses aortic stiffening, and mitigates vascular inflammation with agingZachary S Clayton, David A Hutton, Vienna E Brunt, et al.
Hypertension (Dallas, Tex. : 1979)|June 11, 2020
Trimethylamine-N-Oxide Promotes Age-Related Vascular Oxidative Stress and Endothelial Dysfunction in Mice and Healthy HumansVienna E Brunt, Rachel A Gioscia-Ryan, Abigail G Casso, et al.
American Journal of Physiology. Heart and Circulatory Physiology|October 27, 2025
Cellular senescence mediates doxorubicin chemotherapy-induced vascular endothelial dysfunction: translational evidence of prevention with senolytic treatmentRavinandan Venkatasubramanian, Sophia A Mahoney, David A Hutton, et al.
Aging Biology|February 3, 2025
Oral Supplementation with the Short-Chain Fatty Acid Acetate Ameliorates Age-Related Arterial Dysfunction in MiceAbigail G Longtine, Nathan T Greenberg, Antonio Gonzalez, et al.
Aging Cell|December 8, 2023
Intermittent supplementation with fisetin improves arterial function in old mice by decreasing cellular senescenceSophia A Mahoney, Ravinandan Venkatasubramanian, Mary A Darrah, et al.
Hypertension (Dallas, Tex. : 1979)|January 12, 2026
Late-Onset Menopause and Attenuated Aortic StiffnessSanna Darvish, Kevin O Murray, Sophia A Mahoney, et al.
Aging Cell|April 23, 2026
Senolytic Treatment With Fisetin Reverses Age-Related Endothelial Dysfunction Partially Mediated by SASP Factor CXCL12Sophia A Mahoney, Krystyna Mazan-Mamczarz, Dimitrios Tsitsipatis, et al.
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