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Molecular Pharmacology|July 3, 2015
Quantitative Signaling and Structure-Activity Analyses Demonstrate Functional Selectivity at the Nociceptin/Orphanin FQ Opioid ReceptorSteven D Chang, S Wayne Mascarella, Skylar M Spangler, et al.Journal of Medicinal Chemistry|October 23, 2013
4β-Methyl-5-(3-hydroxyphenyl)morphan opioid agonist and partial agonist derived from a 4β-methyl-5-(3-hydroxyphenyl)morphan pure antagonistF Ivy Carroll, Moses G Gichinga, John D Williams, et al.Journal of Medicinal Chemistry|January 9, 2004
Discovery of the first N-substituted 4beta-methyl-5-(3-hydroxyphenyl)morphan to possess highly potent and selective opioid delta receptor antagonist activityF Ivy Carroll, Li Zhang, S Wayne Mascarella, et al.ACS Chemical Neuroscience|October 12, 2016
Synthesis, Nicotinic Acetylcholine Receptor Binding, and in Vitro and in Vivo Pharmacological Properties of 2'-Fluoro-(substituted thiophenyl)deschloroepibatidine AnaloguesPauline W Ondachi, Ana H Castro, Benjamin Sherman, et al.Bioorganic & Medicinal Chemistry|August 3, 2015
Synthesis, nicotinic acetylcholine receptor binding, in vitro and in vivo pharmacology properties of 3'-(substituted pyridinyl)-deschloroepibatidine analogsPauline W Ondachi, Zhuo Ye, Ana H Castro, et al.Journal of Medicinal Chemistry|June 16, 2007
Synthesis and pharmacological evaluation of phenylethynyl[1,2,4]methyltriazines as analogues of 3-methyl-6-(phenylethynyl)pyridineF Ivy Carroll, Sharadsrikar V Kotturi, Hernán A Navarro, et al.Journal of Medicinal Chemistry|January 17, 2014
Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2'-fluoro-3'-(substituted pyridinyl)-7-deschloroepibatidine analoguesPauline W Ondachi, Ana H Castro, Jakub M Bartkowiak, et al.Journal of Medicinal Chemistry|February 6, 2004
Importance of phenolic address groups in opioid kappa receptor selective antagonistsJames B Thomas, Scott E Fix, Richard B Rothman, et al.Bioorganic & Medicinal Chemistry|July 2, 2016
Design, synthesis, and pharmacological evaluation of JDTic analogs to examine the significance of replacement of the 3-hydroxyphenyl group with pyridine or thiophene bioisosteresChad M Kormos, Moses G Gichinga, Scott P Runyon, et al.ACS Medicinal Chemistry Letters|July 26, 2017
Simple Tetrahydroisoquinolines Are Potent and Selective Kappa Opioid Receptor AntagonistsChad M Kormos, Pauline W Ondachi, Scott P Runyon, et al.Pageof 5