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Journal of Medicinal Chemistry|June 24, 2010

Analogues of (3R)-7-hydroxy-N-[(1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide (JDTic). Synthesis and in vitro and in vivo opioid receptor antagonist activityScott P Runyon, Lawrence E Brieaddy, S Wayne Mascarella, et al.

The Journal of Organic Chemistry|July 28, 2016

Design, Synthesis, and Biological Evaluation of Structurally Rigid Analogues of 4-(3-Hydroxyphenyl)piperidine Opioid Receptor AntagonistsScott P Runyon, Chad M Kormos, Moses G Gichinga, et al.

Journal of Medicinal Chemistry|November 13, 2007

Synthesis and nicotinic acetylcholine receptor binding properties of bridged and fused ring analogues of epibatidineF Ivy Carroll, T Philip Robinson, Lawrence E Brieaddy, et al.

Journal of Medicinal Chemistry|February 16, 2011

Synthesis of 2-(substituted phenyl)-3,5,5-trimethylmorpholine analogues and their effects on monoamine uptake, nicotinic acetylcholine receptor function, and behavioral effects of nicotineF Ivy Carroll, Ana Z Muresan, Bruce E Blough, et al.

Bioorganic & Medicinal Chemistry|September 7, 2015

Design, synthesis, and pharmacological evaluation of JDTic analogs to examine the significance of the 3- and 4-methyl substituentsF Ivy Carroll, Moses G Gichinga, Chad M Kormos, et al.

ACS Chemical Neuroscience|April 21, 2015

In vitro and in vivo neuronal nicotinic receptor properties of (+)- and (-)-pyrido[3,4]homotropane [(+)- and (-)-PHT]: (+)-PHT is a potent and selective full agonist at α6β2 containing neuronal nicotinic acetylcholine receptorsF Ivy Carroll, Hernán A Navarro, S Wayne Mascarella, et al.

ACS Chemical Neuroscience|November 21, 2017

Caged Naloxone: Synthesis, Characterization, and Stability of 3- O-(4,5-Dimethoxy-2-nitrophenyl)carboxymethyl Naloxone (CNV-NLX)Anita H Lewin, Scott E Fix, Desong Zhong, et al.

Journal of Medicinal Chemistry|August 19, 2014

Design, synthesis, and biological evaluation of (3R)-1,2,3,4-tetrahydro-7-hydroxy-N-[(1S)-1-[[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-2-methylpropyl]-3-isoquinolinecarboxamide (JDTic) analogues: in vitro pharmacology and ADME profileChad M Kormos, Moses G Gichinga, Rangan Maitra, et al.

ACS Chemical Neuroscience|May 12, 2016

Synthesis, Nicotinic Acetylcholine Binding, and in Vitro and in Vivo Pharmacological Properties of 2'-Fluoro-(carbamoylpyridinyl)deschloroepibatidine AnaloguesPauline W Ondachi, Ana H Castro, Charles W Luetje, et al.

Bioorganic Chemistry|May 25, 2021

α-[Amino(4-aminophenyl)thio]methylene-2-(trifluoromethyl)benzeneacetonitrile; Configurational equilibria in solutionCharles J McElhinny, Anita H Lewin, Larry Brieaddy, et al.

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Showing results (31-40 of 48) with videos related to

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Journal of Medicinal Chemistry|June 24, 2010

Analogues of (3R)-7-hydroxy-N-[(1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide (JDTic). Synthesis and in vitro and in vivo opioid receptor antagonist activityScott P Runyon, Lawrence E Brieaddy, S Wayne Mascarella, et al.

The Journal of Organic Chemistry|July 28, 2016

Design, Synthesis, and Biological Evaluation of Structurally Rigid Analogues of 4-(3-Hydroxyphenyl)piperidine Opioid Receptor AntagonistsScott P Runyon, Chad M Kormos, Moses G Gichinga, et al.

Journal of Medicinal Chemistry|November 13, 2007

Synthesis and nicotinic acetylcholine receptor binding properties of bridged and fused ring analogues of epibatidineF Ivy Carroll, T Philip Robinson, Lawrence E Brieaddy, et al.

Journal of Medicinal Chemistry|February 16, 2011

Synthesis of 2-(substituted phenyl)-3,5,5-trimethylmorpholine analogues and their effects on monoamine uptake, nicotinic acetylcholine receptor function, and behavioral effects of nicotineF Ivy Carroll, Ana Z Muresan, Bruce E Blough, et al.

Bioorganic & Medicinal Chemistry|September 7, 2015

Design, synthesis, and pharmacological evaluation of JDTic analogs to examine the significance of the 3- and 4-methyl substituentsF Ivy Carroll, Moses G Gichinga, Chad M Kormos, et al.

ACS Chemical Neuroscience|April 21, 2015

In vitro and in vivo neuronal nicotinic receptor properties of (+)- and (-)-pyrido[3,4]homotropane [(+)- and (-)-PHT]: (+)-PHT is a potent and selective full agonist at α6β2 containing neuronal nicotinic acetylcholine receptorsF Ivy Carroll, Hernán A Navarro, S Wayne Mascarella, et al.

ACS Chemical Neuroscience|November 21, 2017

Caged Naloxone: Synthesis, Characterization, and Stability of 3- O-(4,5-Dimethoxy-2-nitrophenyl)carboxymethyl Naloxone (CNV-NLX)Anita H Lewin, Scott E Fix, Desong Zhong, et al.

Journal of Medicinal Chemistry|August 19, 2014

Design, synthesis, and biological evaluation of (3R)-1,2,3,4-tetrahydro-7-hydroxy-N-[(1S)-1-[[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-2-methylpropyl]-3-isoquinolinecarboxamide (JDTic) analogues: in vitro pharmacology and ADME profileChad M Kormos, Moses G Gichinga, Rangan Maitra, et al.

ACS Chemical Neuroscience|May 12, 2016

Synthesis, Nicotinic Acetylcholine Binding, and in Vitro and in Vivo Pharmacological Properties of 2'-Fluoro-(carbamoylpyridinyl)deschloroepibatidine AnaloguesPauline W Ondachi, Ana H Castro, Charles W Luetje, et al.

Bioorganic Chemistry|May 25, 2021

α-[Amino(4-aminophenyl)thio]methylene-2-(trifluoromethyl)benzeneacetonitrile; Configurational equilibria in solutionCharles J McElhinny, Anita H Lewin, Larry Brieaddy, et al.

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