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Cancer Research|November 27, 2015
Agonists of the TRAIL Death Receptor DR5 Sensitize Intestinal Stem Cells to Chemotherapy-Induced Cell Death and Trigger Gastrointestinal ToxicityNiklas K Finnberg, Prashanth Gokare, Arunasalam Navaraj, et al.
Cancer Biology & Therapy|July 5, 2011
Quinacrine synergizes with 5-fluorouracil and other therapies in colorectal cancerJean-Nicolas Gallant, Joshua E Allen, Charles D Smith, et al.
Cancer Biology & Therapy|June 25, 2013
FOLFIRI plus dulanermin (rhApo2L/TRAIL) in a patient with BRAF-mutant metastatic colon cancerBora Lim, Angelique Scicchitano, Cheryl Beachler, et al.
Molecular Cancer Therapeutics|December 10, 2009
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and paclitaxel have cooperative in vivo effects against glioblastoma multiforme cellsJay F Dorsey, Akiva Mintz, Xiaobing Tian, et al.
Cell Cycle (Georgetown, Tex.)|August 17, 2012
Mitomycin C potentiates TRAIL-induced apoptosis through p53-independent upregulation of death receptors: evidence for the role of c-Jun N-terminal kinase activationHairong Cheng, Bo Hong, Lanlan Zhou, et al.
Cancer Biology & Therapy|September 21, 2011
Preliminary observations indicate variable patterns of plasma 5-fluorouracil (5-FU) levels during dose optimization of infusional 5-FU in colorectal cancer patientsChristina Leah Kline, Hassan S Sheikh, Angelique Scicchitano, et al.
Cell Cycle (Georgetown, Tex.)|January 8, 2010
The p53 target Plk2 interacts with TSC proteins impacting mTOR signaling, tumor growth and chemosensitivity under hypoxic conditionsElizabeth M Matthew, Lori S Hart, Aristotelis Astrinidis, et al.
Science Signaling|February 18, 2016
ONC201 kills solid tumor cells by triggering an integrated stress response dependent on ATF4 activation by specific eIF2α kinasesC Leah B Kline, A Pieter J Van den Heuvel, Joshua E Allen, et al.
The Journal of Biological Chemistry|September 13, 2005
Glucocorticoid-induced tumor necrosis factor receptor is a p21Cip1/WAF1 transcriptional target conferring resistance of keratinocytes to UV light-induced apoptosisJian Wang, Vikram Devgan, Marcella Corrado, et al.
American Journal of Cancer Research|October 18, 2021
Potent preclinical sensitivity to imipridone-based combination therapies in oncohistone H3K27M-mutant diffuse intrinsic pontine glioma is associated with induction of the integrated stress response, TRAIL death receptor DR5, reduced ClpX and apoptosisRobyn Borsuk, Lanlan Zhou, Wen-I Chang, et al.
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