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Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research|February 24, 2001
Antagonism of the osteoclast vitronectin receptor with an orally active nonpeptide inhibitor prevents cancellous bone loss in the ovariectomized ratM W Lark, G B Stroup, R A Dodds, et al.Bone|September 12, 2006
A highly potent inhibitor of cathepsin K (relacatib) reduces biomarkers of bone resorption both in vitro and in an acute model of elevated bone turnover in vivo in monkeysS Kumar, L Dare, J A Vasko-Moser, et al.Bone|May 9, 2002
A potent small molecule, nonpeptide inhibitor of cathepsin K (SB 331750) prevents bone matrix resorption in the ovariectomized ratMichael W Lark, G B Stroup, I E James, et al.The Journal of Biological Chemistry|June 8, 1999
Identification and cloning of a connective tissue growth factor-like cDNA from human osteoblasts encoding a novel regulator of osteoblast functionsS Kumar, A T Hand, J R Connor, et al.The Journal of Pharmacology and Experimental Therapeutics|October 19, 1999
Design and characterization of orally active Arg-Gly-Asp peptidomimetic vitronectin receptor antagonist SB 265123 for prevention of bone loss in osteoporosisM W Lark, G B Stroup, S M Hwang, et al.Bioorganic & Medicinal Chemistry Letters|January 5, 1999
Benzimidazole derivatives as arginine mimetics in 1,4-benzodiazepine nonpeptide vitronectin receptor (alpha v beta 3) antagonistsR M Keenan, W H Miller, M A Lago, et al.Bioorganic & Medicinal Chemistry Letters|January 5, 1999
Discovery of an imidazopyridine-containing 1,4-benzodiazepine nonpeptide vitronectin receptor (alpha v beta 3) antagonist with efficacy in a restenosis modelR M Keenan, M A Lago, W H Miller, et al.Journal of Medicinal Chemistry|March 3, 1999
Conformational preferences in a benzodiazepine series of potent nonpeptide fibrinogen receptor antagonistsR M Keenan, J F Callahan, J M Samanen, et al.Bioorganic & Medicinal Chemistry Letters|July 16, 1999
Orally bioavailable nonpeptide vitronectin receptor antagonists with efficacy in an osteoporosis modelW H Miller, W E Bondinell, R D Cousins, et al.Journal of Medicinal Chemistry|April 20, 2001
Azepanone-based inhibitors of human and rat cathepsin KR W Marquis, Y Ru, S M LoCastro, et al.Pageof 10