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The Lancet. Diabetes & Endocrinology|June 24, 2026
Whole-population trends in obesity across dimensions of inequality in England, 2019-25: a retrospective, longitudinal cohort study of 54 million adultsRobert A Fletcher, Nathalie Conrad, Patrick Rockenschaub, et al.American Journal of Human Genetics|June 30, 2009
Loss-of-function mutation in the dioxygenase-encoding FTO gene causes severe growth retardation and multiple malformationsSarah Boissel, Orit Reish, Karine Proulx, et al.The Lancet. Diabetes & Endocrinology|November 2, 2020
Efficacy and safety of setmelanotide, an MC4R agonist, in individuals with severe obesity due to LEPR or POMC deficiency: single-arm, open-label, multicentre, phase 3 trialsKarine Clément, Erica van den Akker, Jesús Argente, et al.The Journal of Clinical Endocrinology and Metabolism|August 12, 2011
Novel FGF8 mutations associated with recessive holoprosencephaly, craniofacial defects, and hypothalamo-pituitary dysfunctionMark J McCabe, Carles Gaston-Massuet, Vaitsa Tziaferi, et al.The Journal of Clinical Endocrinology and Metabolism|February 9, 2022
Obesity Due to Steroid Receptor Coactivator-1 Deficiency Is Associated With Endocrine and Metabolic AbnormalitiesTessa M Cacciottolo, Elana Henning, Julia M Keogh, et al.Diabetes|November 30, 2006
Hyperphagia, severe obesity, impaired cognitive function, and hyperactivity associated with functional loss of one copy of the brain-derived neurotrophic factor (BDNF) geneJuliette Gray, Giles S H Yeo, James J Cox, et al.Scientific Reports|June 5, 2020
Human BDNF/TrkB variants impair hippocampal synaptogenesis and associate with neurobehavioural abnormalitiesTakuhiro Sonoyama, Lukas K J Stadler, Mingyan Zhu, et al.Endocrinology|June 28, 2014
Functional characterization of obesity-associated variants involving the α and β isoforms of human SH2B1Laura R Pearce, Ray Joe, Michael E Doche, et al.Clinical Obesity|April 11, 2024
IMPROVE 2022 International Meeting on Pathway-Related Obesity: Vision of ExcellencePeter Kühnen, Jesús Argente, Karine Clément, et al.The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|April 30, 2010
CNS leptin action modulates immune response and survival in sepsisJohannes Tschöp, Ruben Nogueiras, Sarah Haas-Lockie, et al.Pageof 23