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Journal of Molecular Biology|April 17, 2023
Designed Loop Extension Followed by Combinatorial Screening Confers High Specificity to a Broad Matrix MetalloproteinaseInhibitorAlessandro Bonadio, Bernhard L Wenig, Alexandra Hockla, et al.Journal of Molecular Biology|November 29, 2016
Identifying Residues that Determine SCF Molecular-Level Interactions through a Combination of Experimental and In silico AnalysesEitan Rabinovich, Michael Heyne, Anna Bakhman, et al.Journal of Molecular Biology|April 6, 2010
What makes Ras an efficient molecular switch: a computational, biophysical, and structural study of Ras-GDP interactions with mutants of RafDaniel Filchtinski, Oz Sharabi, Alma Rüppel, et al.Proceedings of the National Academy of Sciences of the United States of America|September 13, 2006
Ca2+/calmodulin-dependent protein kinase II (CaMKII) is activated by calmodulin with two bound calciumsJulia M Shifman, Mee H Choi, Stefan Mihalas, et al.The Journal of Biological Chemistry|October 17, 2024
Engineered TIMP2 with narrow MMP-9 specificity is an effective inhibitor of invasion and proliferation of triple-negative breast cancer cellsNaama Rotenberg, Mark Feldman, Jason Shirian, et al.The Journal of Biological Chemistry|October 31, 2021
Engineered variants of the Ras effector protein RASSF5 (NORE1A) promote anticancer activities in lung adenocarcinomaAnamika Singh, Ariel Erijman, Ashish Noronha, et al.Journal of the American Chemical Society|October 5, 2021
Climbing Up and Down Binding Landscapes through Deep Mutational Scanning of Three Homologous Protein-Protein ComplexesMichael Heyne, Jason Shirian, Itay Cohen, et al.FEBS Letters|February 24, 2018
Converting a broad matrix metalloproteinase family inhibitor into a specific inhibitor of MMP-9 and MMP-14Jason Shirian, Valeria Arkadash, Itay Cohen, et al.Science Signaling|October 14, 2020
RASSF effectors couple diverse RAS subfamily GTPases to the Hippo pathwayThillaivillalan Dhanaraman, Swati Singh, Ryan C Killoran, et al.Protein Engineering, Design & Selection : PEDS|August 1, 2009
Design, expression and characterization of mutants of fasciculin optimized for interaction with its target, acetylcholinesteraseOz Sharabi, Yoav Peleg, Efrat Mashiach, et al.Pageof 5