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Nature Communications
|
May 27, 2024
Apo and Aβ46-bound γ-secretase structures provide insights into amyloid-β processing by the APH-1B isoform
Ivica Odorčić, Mohamed Belal Hamed, Sam Lismont, et al.
The Journal of Biological Chemistry
|
December 17, 2013
Signature amyloid β profiles are produced by different γ-secretase complexes
Hermien Acx, Lucía Chávez-Gutiérrez, Lutgarde Serneels, et al.
The EMBO Journal
|
October 19, 2023
APP substrate ectodomain defines amyloid-β peptide length by restraining γ-secretase processivity and facilitating product release
Matthias Koch, Thomas Enzlein, Shu-Yu Chen, et al.
The EMBO Journal
|
September 19, 2022
Enzyme-substrate interface targeting by imidazole-based γ-secretase modulators activates γ-secretase and stabilizes its interaction with APP
Dieter Petit, Manuel Hitzenberger, Matthias Koch, et al.
The EMBO Journal
|
May 22, 2019
Extracellular interface between APP and Nicastrin regulates Aβ length and response to γ-secretase modulators
Dieter Petit, Manuel Hitzenberger, Sam Lismont, et al.
Journal of Cell Science
|
December 16, 2014
The dynamic conformational landscape of gamma-secretase
Nadav Elad, Bart De Strooper, Sam Lismont, et al.
The Journal of Experimental Medicine
|
October 21, 2015
Qualitative changes in human γ-secretase underlie familial Alzheimer's disease
Maria Szaruga, Sarah Veugelen, Manasi Benurwar, et al.
Biorxiv : the Preprint Server for Biology
|
August 14, 2023
Alzheimer's disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling
Katarzyna Marta Zoltowska, Utpal Das, Sam Lismont, et al.
The EMBO Journal
|
April 17, 2012
The mechanism of γ-Secretase dysfunction in familial Alzheimer disease
Lucía Chávez-Gutiérrez, Leen Bammens, Iryna Benilova, et al.
Elife
|
July 19, 2024
Alzheimer's disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling
Katarzyna Marta Zoltowska, Utpal Das, Sam Lismont, et al.
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of 2
Search research articles
Search
Showing results (1-10 of 11) with videos related to
Sort By:
Page
of 2
Nature Communications
|
May 27, 2024
Apo and Aβ46-bound γ-secretase structures provide insights into amyloid-β processing by the APH-1B isoform
Ivica Odorčić, Mohamed Belal Hamed, Sam Lismont, et al.
The Journal of Biological Chemistry
|
December 17, 2013
Signature amyloid β profiles are produced by different γ-secretase complexes
Hermien Acx, Lucía Chávez-Gutiérrez, Lutgarde Serneels, et al.
The EMBO Journal
|
October 19, 2023
APP substrate ectodomain defines amyloid-β peptide length by restraining γ-secretase processivity and facilitating product release
Matthias Koch, Thomas Enzlein, Shu-Yu Chen, et al.
The EMBO Journal
|
September 19, 2022
Enzyme-substrate interface targeting by imidazole-based γ-secretase modulators activates γ-secretase and stabilizes its interaction with APP
Dieter Petit, Manuel Hitzenberger, Matthias Koch, et al.
The EMBO Journal
|
May 22, 2019
Extracellular interface between APP and Nicastrin regulates Aβ length and response to γ-secretase modulators
Dieter Petit, Manuel Hitzenberger, Sam Lismont, et al.
Journal of Cell Science
|
December 16, 2014
The dynamic conformational landscape of gamma-secretase
Nadav Elad, Bart De Strooper, Sam Lismont, et al.
The Journal of Experimental Medicine
|
October 21, 2015
Qualitative changes in human γ-secretase underlie familial Alzheimer's disease
Maria Szaruga, Sarah Veugelen, Manasi Benurwar, et al.
Biorxiv : the Preprint Server for Biology
|
August 14, 2023
Alzheimer's disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling
Katarzyna Marta Zoltowska, Utpal Das, Sam Lismont, et al.
The EMBO Journal
|
April 17, 2012
The mechanism of γ-Secretase dysfunction in familial Alzheimer disease
Lucía Chávez-Gutiérrez, Leen Bammens, Iryna Benilova, et al.
Elife
|
July 19, 2024
Alzheimer's disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling
Katarzyna Marta Zoltowska, Utpal Das, Sam Lismont, et al.
Page
of 2