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Oncoimmunology|January 3, 2024
A phase 2, multicenter, open-label study of anti-LAG-3 ieramilimab in combination with anti-PD-1 spartalizumab in patients with advanced solid malignanciesChia-Chi Lin, Elena Garralda, Patrick Schöffski, et al.Biochemical and Biophysical Research Communications|November 21, 2022
Dual PI3Kδγ inhibition demonstrates potent anticancer effects in diffuse large B-cell lymphoma models: Discovery and preclinical characterization of LL-00084282Mahip K Verma, Charudatt Samant, Ramesh Kale, et al.Journal for Immunotherapy of Cancer|February 26, 2022
Phase I/II study of the LAG-3 inhibitor ieramilimab (LAG525) ± anti-PD-1 spartalizumab (PDR001) in patients with advanced malignanciesPatrick Schöffski, Daniel S W Tan, Miguel Martín, et al.Cell Reports|October 21, 2020
Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant MelanomaMayinuer Maitituoheti, Emily Z Keung, Ming Tang, et al.Proceedings of the National Academy of Sciences of the United States of America|May 25, 2005
Rapid identification and strain-typing of respiratory pathogens for epidemic surveillanceDavid J Ecker, Rangarajan Sampath, Lawrence B Blyn, et al.Bioorganic & Medicinal Chemistry Letters|June 20, 2013
Orally available and efficacious α4β1/α4β7 integrin inhibitorsYing-zi Xu, Jenifer L Smith, Christopher M Semko, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|November 19, 2020
Identification of a Synthetic Lethal Relationship between Nucleotide Excision Repair Deficiency and Irofulven Sensitivity in Urothelial CancerJudit Börcsök, Zsofia Sztupinszki, Raie Bekele, et al.Bioorganic & Medicinal Chemistry Letters|September 14, 2010
Design of an orally efficacious hydroxyethylamine (HEA) BACE-1 inhibitor in a preclinical animal modelAnh P Truong, Gergley Tóth, Gary D Probst, et al.Bioorganic & Medicinal Chemistry Letters|August 5, 2011
Design and synthesis of brain penetrant selective JNK inhibitors with improved pharmacokinetic properties for the prevention of neurodegenerationSimeon Bowers, Anh P Truong, R Jeffrey Neitz, et al.Radiology|April 26, 2022
Quantitative CT Characteristics of Cluster Phenotypes in the Severe Asthma Research Program CohortsAbhaya P Trivedi, Chase Hall, Charles W Goss, et al.Pageof 107