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Journal of Pharmaceutical Sciences|December 18, 2020
Evaluation of Prediction Accuracy for Volume of Distribution in Rat and Human Using In Vitro, In Vivo, PBPK and QSAR MethodsShibin Mathew, David Tess, Woodrow Burchett, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|February 22, 2024
Low molecular weight acids and OATP1B mediated hepatic clearance: In vitro and in vivo evaluation using novel hypoxia-inducible factor prolyl hydroxylase inhibitors (Dustats)Yi-An Bi, Samantha Jordan, Amanda King-Ahmad, et al.
The AAPS Journal|March 28, 2024
Novel Multiplexed High Throughput Screening of Selective Inhibitors for Drug-Metabolizing Enzymes Using Human HepatocytesJianhua Liu, Daria Vernikovskaya, Gary Bora, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|April 26, 2025
Applications of contemporary tools to measure plasma protein binding of targeted protein degradersMark Niosi, Sam Zhang, Woodrow Burchett, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|September 14, 2020
Mechanistic insights on clearance and inhibition discordance between liver microsomes and hepatocytes when clearance in liver microsomes is higher than in hepatocytesChristopher Keefer, George Chang, Anthony Carlo, et al.
Nature Communications|January 2, 2025
Design and application of synthetic 17B-HSD13 substrates reveals preserved catalytic activity of protective human variantsMichelle R Garnsey, Yang Wang, David J Edmonds, et al.
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