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Cell Chemical Biology|July 28, 2021
A structure-specific small molecule inhibits a miRNA-200 family member precursor and reverses a type 2 diabetes phenotypeHafeez S Haniff, Xiaohui Liu, Yuquan Tong, et al.Chemical Society Reviews|September 16, 2020
Design of small molecules targeting RNA structure from sequenceAndrei Ursu, Jessica L Childs-Disney, Ryan J Andrews, et al.Journal of the American Chemical Society|November 7, 2022
DNA-Encoded Library Screening To Inform Design of a Ribonuclease Targeting Chimera (RiboTAC)Samantha M Meyer, Toru Tanaka, Patrick R A Zanon, et al.Journal of the American Chemical Society|August 13, 2021
Reprogramming of Protein-Targeted Small-Molecule Medicines to RNA by Ribonuclease RecruitmentPeiyuan Zhang, Xiaohui Liu, Daniel Abegg, et al.Journal of the American Chemical Society|October 6, 2025
Covalent Probes Reveal Small-Molecule Binding Pockets in Structured RNA and Enable Bioactive Compound DesignSandra Kovachka, Jielei Wang, Amirhossein Taghavi, et al.Proceedings of the National Academy of Sciences of the United States of America|November 21, 2022
A blood-brain penetrant RNA-targeted small molecule triggers elimination of r(G4C2)exp in c9ALS/FTD via the nuclear RNA exosomeJessica A Bush, Samantha M Meyer, Rita Fuerst, et al.Science Translational Medicine|October 27, 2021
Ribonuclease recruitment using a small molecule reduced c9ALS/FTD r(G4C2) repeat expansion in vitro and in vivo ALS modelsJessica A Bush, Haruo Aikawa, Rita Fuerst, et al.Pageof 2