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Journal of Pharmacokinetics and Pharmacodynamics|October 8, 2021
Exposure-response modeling improves selection of radiation and radiosensitizer combinationsTim Cardilin, Joachim Almquist, Mats Jirstrand, et al.
BMC Cancer|May 6, 2023
Model-based assessment of combination therapies - ranking of radiosensitizing agents in oncologyMarcus Baaz, Tim Cardilin, Floriane Lignet, et al.
Journal of Lipid Research|January 17, 2002
Substrate specificity of rat brain ceramidaseSamer El Bawab, Julnar Usta, Patrick Roddy, et al.
The Biochemical Journal|October 19, 2005
Identification of a novel amidase motif in neutral ceramidaseSehamuddin Galadari, Bill X Wu, Cungui Mao, et al.
The AAPS Journal|September 30, 2016
Tumor Static Concentration Curves in Combination TherapyTim Cardilin, Joachim Almquist, Mats Jirstrand, et al.
The Biochemical Journal|November 2, 2004
A mitochondrial pool of sphingomyelin is involved in TNFalpha-induced Bax translocation to mitochondriaHelene Birbes, Chiara Luberto, Yi-Te Hsu, et al.
CPT: Pharmacometrics & Systems Pharmacology|October 13, 2018
A Novel PBPK Modeling Approach to Assess Cytochrome P450 Mediated Drug-Drug Interaction Potential of the Cytotoxic Prodrug EvofosfamideChristian Lüpfert, Martin Dyroff, Oliver von Richter, et al.
Clinical Pharmacology and Therapeutics|January 20, 2020
Selection of the Recommended Phase 2 Dose for Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting TGF-β and PD-L1Yulia Vugmeyster, Justin Wilkins, Andre Koenig, et al.
The Journal of Biological Chemistry|June 12, 2003
Purification, characterization, and identification of a sphingomyelin synthase from Pseudomonas aeruginosa. PlcH is a multifunctional enzymeChiara Luberto, Martin J Stonehouse, Elizabeth A Collins, et al.
CPT: Pharmacometrics & Systems Pharmacology|April 5, 2021
Translational pharmacokinetic-pharmacodynamic modeling of preclinical and clinical data of the oral MET inhibitor tepotinib to determine the recommended phase II doseWenyuan Xiong, Manja Friese-Hamim, Andreas Johne, et al.
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