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Biochemistry|October 17, 2019
Bimodal Actions of a Naphthyridone/Aminopiperidine-Based Antibacterial That Targets Gyrase and Topoisomerase IVElizabeth G Gibson, Alexandria A Oviatt, Monica Cacho, et al.
Nucleic Acids Research|September 22, 2017
Activities of gyrase and topoisomerase IV on positively supercoiled DNARachel E Ashley, Andrew Dittmore, Sylvia A McPherson, et al.
Nucleic Acids Research|March 23, 2011
Direct measurement of DNA bending by type IIA topoisomerases: implications for non-equilibrium topology simplificationAshley H Hardin, Susanta K Sarkar, Yeonee Seol, et al.
Biochemistry|March 19, 2011
Interactions between the etoposide derivative F14512 and human type II topoisomerases: implications for the C4 spermine moiety in promoting enzyme-mediated DNA cleavageAmanda C Gentry, Steven L Pitts, Michael J Jablonsky, et al.
Biochemistry|October 4, 2014
Catalytic core of human topoisomerase IIα: insights into enzyme-DNA interactions and drug mechanismR Hunter Lindsey, MaryJean Pendleton, Rachel E Ashley, et al.
Nucleic Acids Research|February 16, 2018
Coupling the core of the anticancer drug etoposide to an oligonucleotide induces topoisomerase II-mediated cleavage at specific DNA sequencesLorena Infante Lara, Sabine Fenner, Steven Ratcliffe, et al.
Biochemistry|July 15, 2017
Interactions between Quinolones and Bacillus anthracis Gyrase and the Basis of Drug ResistanceRachel E Ashley, R Hunter Lindsey, Sylvia A McPherson, et al.
Antimicrobial Agents and Chemotherapy|September 24, 2014
Bacillus anthracis GrlAV96A topoisomerase IV, a quinolone resistance mutation that does not affect the water-metal ion bridgeKatie J Aldred, Erin J Breland, Sylvia A McPherson, et al.
ACS Infectious Diseases|October 9, 2025
Mechanism of Action of Gepotidacin: Well-Balanced Dual-Targeting against <i>Neisseria gonorrhoeae</i> Gyrase and Topoisomerase IV in Cells and In VitroAlexandria A Oviatt, Jessica A Collins, Chelsea A Mann, et al.
ACS Infectious Diseases|April 12, 2024
Interactions between Gepotidacin and <i>Escherichia coli</i> Gyrase and Topoisomerase IV: Genetic and Biochemical Evidence for Well-Balanced Dual-TargetingAlexandria A Oviatt, Elizabeth G Gibson, Jianzhong Huang, et al.
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