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Frontiers in Pharmacology|March 19, 2020
Modulation of hERG K+ Channel Deactivation by Voltage Sensor RelaxationYu Patrick Shi, Samrat Thouta, Thomas W ClaydonScientific Reports|March 23, 2018
Investigating the state dependence of drug binding in hERG channels using a trapped-open channel phenotypeSamrat Thouta, Garman Lo, Lukas Grajauskas, et al.Scientific Reports|July 27, 2021
Kv1.1 channels mediate network excitability and feed-forward inhibition in local amygdala circuitsSamrat Thouta, Yiming Zhang, Esperanza Garcia, et al.The Journal of General Physiology|December 12, 2018
Extracellular protons accelerate hERG channel deactivation by destabilizing voltage sensor relaxationYu Patrick Shi, Samrat Thouta, Yen May Cheng, et al.Biophysical Journal|March 11, 2014
Proline scan of the HERG channel S6 helix reveals the location of the intracellular pore gateSamrat Thouta, Stanislav Sokolov, Yuki Abe, et al.The Journal of Biological Chemistry|December 8, 2010
Mechanistic insight into human ether-à-go-go-related gene (hERG) K+ channel deactivation gating from the solution structure of the EAG domainFrederick W Muskett, Samrat Thouta, Steven J Thomson, et al.Biophysical Journal|January 26, 2017
Stabilization of the Activated hERG Channel Voltage Sensor by Depolarization Involves the S4-S5 LinkerSamrat Thouta, Christina M Hull, Yu Patrick Shi, et al.Frontiers in Cellular Neuroscience|October 17, 2022
Pharmacological determination of the fractional block of Nav channels required to impair neuronal excitability and ex vivo seizuresSamrat Thouta, Matthew G Waldbrook, Sophia Lin, et al.Biophysical Journal|March 27, 2015
NS1643 interacts around L529 of hERG to alter voltage sensor movement on the path to activationJiqing Guo, Yen May Cheng, James P Lees-Miller, et al.Cell Reports|November 21, 2019
The X-Linked Intellectual Disability Gene Zdhhc9 Is Essential for Dendrite Outgrowth and Inhibitory Synapse FormationJordan J Shimell, Bhavin S Shah, Stuart M Cain, et al.Pageof 2