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Disease Models & Mechanisms|November 9, 2011
Set points, settling points and some alternative models: theoretical options to understand how genes and environments combine to regulate body adiposityJohn R Speakman, David A Levitsky, David B Allison, et al.Molecular Metabolism|October 17, 2017
Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiencyTinh-Hai Collet, Béatrice Dubern, Jacek Mokrosinski, et al.The Journal of Clinical Investigation|September 22, 2007
The central melanocortin system directly controls peripheral lipid metabolismRuben Nogueiras, Petra Wiedmer, Diego Perez-Tilve, et al.Elife|April 18, 2017
Human biallelic MFN2 mutations induce mitochondrial dysfunction, upper body adipose hyperplasia, and suppression of leptin expressionNuno Rocha, David A Bulger, Andrea Frontini, et al.Nature Genetics|June 26, 2012
Mosaic overgrowth with fibroadipose hyperplasia is caused by somatic activating mutations in PIK3CAMarjorie J Lindhurst, Victoria E R Parker, Felicity Payne, et al.Plos Medicine|November 30, 2016
Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation AnalysisLuca A Lotta, Robert A Scott, Stephen J Sharp, et al.Cell|January 30, 2016
Trim28 Haploinsufficiency Triggers Bi-stable Epigenetic ObesityKevin Dalgaard, Kathrin Landgraf, Steffen Heyne, et al.Scientific Reports|July 1, 2017
Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood ObesityAudrey E Hendricks, Elena G Bochukova, Gaëlle Marenne, et al.Nature Genetics|November 15, 2016
Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistanceLuca A Lotta, Pawan Gulati, Felix R Day, et al.The Journal of Clinical Endocrinology and Metabolism|December 7, 2021
Identification of Rare Loss-of-Function Genetic Variation Regulating Body Fat DistributionMine Koprulu, Yajie Zhao, Eleanor Wheeler, et al.Pageof 30