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Expert Opinion on Drug Metabolism & Toxicology|April 9, 2011
The effect of therapeutic hypothermia on drug metabolism and response: cellular mechanisms to organ functionJiangquan Zhou, Samuel M Poloyac
Critical Care Medicine|September 15, 2007
Effects of hypothermia on drug disposition, metabolism, and response: A focus of hypothermia-mediated alterations on the cytochrome P450 enzyme systemMichael A Tortorici, Patrick M Kochanek, Samuel M Poloyac
Journal of Neuroscience Methods|May 25, 2005
Identification and quantification of the hydroxyeicosatetraenoic acids, 20-HETE and 12-HETE, in the cerebrospinal fluid after subarachnoid hemorrhageSamuel M Poloyac, Robert B Reynolds, Howard Yonas, et al.
Journal of Neurotrauma|March 1, 2019
Pharmacological Optimization for Successful Traumatic Brain Injury Drug DevelopmentSamuel M Poloyac, Richard J Bertz, Lee A McDermott, et al.
The Journal of Steroid Biochemistry and Molecular Biology|April 27, 2016
A microsomal based method to detect aromatase activity in different brain regions of the rat using ultra performance liquid chromatography-mass spectrometryJunyi Li, Patrick J Oberly, Samuel M Poloyac, et al.
Critical Care Medicine|March 8, 2006
Therapeutic hypothermia-induced pharmacokinetic alterations on CYP2E1 chlorzoxazone-mediated metabolism in a cardiac arrest rat modelMichael A Tortorici, Patrick M Kochanek, Robert R Bies, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences|September 5, 2003
Determination of 20-hydroxyeicosatetraenoic acid in microsomal incubates using high-performance liquid chromatography-mass spectrometry (HPLC-MS)Christopher A Bolcato, Reginald F Frye, Michael A Zemaitis, et al.
Therapeutic Hypothermia and Temperature Management|September 14, 2016
Effect of Hypothermia and Targeted Temperature Management on Drug Disposition and Response Following Cardiac Arrest: A Comprehensive Review of Preclinical and Clinical InvestigationsKacey B Anderson, Samuel M Poloyac, Patrick M Kochanek, et al.
Current Pharmacology Reports|November 1, 2016
A Molecular Aspect in the Regulation of Drug Metabolism: Does PXR-Induced Enzyme Expression Always Lead to Functional Changes in Drug Metabolism?Yuan Wei, Chenxiao Tang, Vinayak Sant, et al.
Critical Care Medicine|December 4, 2008
Moderate hypothermia prevents cardiac arrest-mediated suppression of drug metabolism and induction of interleukin-6 in ratsMichael A Tortorici, Ying Mu, Patrick M Kochanek, et al.
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