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Samuel N Young

Showing results (1-10 of 38) with videos related to

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Cell Death & Disease|April 2, 2021
A family harboring an MLKL loss of function variant implicates impaired necroptosis in diabetesJoanne M Hildebrand, Bernice Lo, Sara Tomei, et al.
The Biochemical Journal|August 13, 2024
Inhibitors identify an auxiliary role for mTOR signalling in necroptosis execution downstream of MLKL activationSarah E Garnish, Christopher R Horne, Yanxiang Meng, et al.
The Biochemical Journal|April 10, 2016
The epigenetic regulator Smchd1 contains a functional GHKL-type ATPase domainKelan Chen, Renwick C J Dobson, Isabelle S Lucet, et al.
Cell Death & Disease|June 23, 2022
Human RIPK3 C-lobe phosphorylation is essential for necroptotic signalingYanxiang Meng, Christopher R Horne, Andre L Samson, et al.
The Biochemical Journal|June 10, 2021
SMCHD1's ubiquitin-like domain is required for N-terminal dimerization and chromatin localizationAlexandra D Gurzau, Christopher R Horne, Yee-Foong Mok, et al.
Growth Factors (Chur, Switzerland)|January 21, 2014
Functional characterization of c-Mpl ectodomain mutations that underlie congenital amegakaryocytic thrombocytopeniaLeila N Varghese, Jian-Guo Zhang, Samuel N Young, et al.
Immunity|February 21, 2012
Suppression of cytokine signaling by SOCS3: characterization of the mode of inhibition and the basis of its specificityJeffrey J Babon, Nadia J Kershaw, James M Murphy, et al.
The Biochemical Journal|August 19, 2015
Necroptosis signalling is tuned by phosphorylation of MLKL residues outside the pseudokinase domain activation loopMaria C Tanzer, Anne Tripaydonis, Andrew I Webb, et al.
Cell Death and Differentiation|February 16, 2018
The brace helices of MLKL mediate interdomain communication and oligomerisation to regulate cell death by necroptosisKatherine A Davies, Maria C Tanzer, Michael D W Griffin, et al.
The Biochemical Journal|December 21, 2013
Mechanistic insights into activation and SOCS3-mediated inhibition of myeloproliferative neoplasm-associated JAK2 mutants from biochemical and structural analysesLeila N Varghese, Daniela Ungureanu, Nicholas P D Liau, et al.
Pageof 4

Showing results (1-10 of 38) with videos related to

Sort By:
Pageof 4
Cell Death & Disease|April 2, 2021
A family harboring an MLKL loss of function variant implicates impaired necroptosis in diabetesJoanne M Hildebrand, Bernice Lo, Sara Tomei, et al.
The Biochemical Journal|August 13, 2024
Inhibitors identify an auxiliary role for mTOR signalling in necroptosis execution downstream of MLKL activationSarah E Garnish, Christopher R Horne, Yanxiang Meng, et al.
The Biochemical Journal|April 10, 2016
The epigenetic regulator Smchd1 contains a functional GHKL-type ATPase domainKelan Chen, Renwick C J Dobson, Isabelle S Lucet, et al.
Cell Death & Disease|June 23, 2022
Human RIPK3 C-lobe phosphorylation is essential for necroptotic signalingYanxiang Meng, Christopher R Horne, Andre L Samson, et al.
The Biochemical Journal|June 10, 2021
SMCHD1's ubiquitin-like domain is required for N-terminal dimerization and chromatin localizationAlexandra D Gurzau, Christopher R Horne, Yee-Foong Mok, et al.
Growth Factors (Chur, Switzerland)|January 21, 2014
Functional characterization of c-Mpl ectodomain mutations that underlie congenital amegakaryocytic thrombocytopeniaLeila N Varghese, Jian-Guo Zhang, Samuel N Young, et al.
Immunity|February 21, 2012
Suppression of cytokine signaling by SOCS3: characterization of the mode of inhibition and the basis of its specificityJeffrey J Babon, Nadia J Kershaw, James M Murphy, et al.
The Biochemical Journal|August 19, 2015
Necroptosis signalling is tuned by phosphorylation of MLKL residues outside the pseudokinase domain activation loopMaria C Tanzer, Anne Tripaydonis, Andrew I Webb, et al.
Cell Death and Differentiation|February 16, 2018
The brace helices of MLKL mediate interdomain communication and oligomerisation to regulate cell death by necroptosisKatherine A Davies, Maria C Tanzer, Michael D W Griffin, et al.
The Biochemical Journal|December 21, 2013
Mechanistic insights into activation and SOCS3-mediated inhibition of myeloproliferative neoplasm-associated JAK2 mutants from biochemical and structural analysesLeila N Varghese, Daniela Ungureanu, Nicholas P D Liau, et al.
Pageof 4