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Samuel N Young

Showing results (21-30 of 38) with videos related to

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Nature Communications|October 26, 2023
Phosphorylation-dependent pseudokinase domain dimerization drives full-length MLKL oligomerizationYanxiang Meng, Sarah E Garnish, Katherine A Davies, et al.
The Biochemical Journal|April 28, 2023
The VEGFR/PDGFR tyrosine kinase inhibitor, ABT-869, blocks necroptosis by targeting RIPK1 kinaseCatia L Pierotti, Annette V Jacobsen, Christoph Grohmann, et al.
The Biochemical Journal|September 26, 2025
Unconventional binding of calmodulin to CHK2 kinase inhibits catalytic activityChristopher R Horne, Tingting Wang, Samuel N Young, et al.
Proceedings of the National Academy of Sciences of the United States of America|April 3, 2020
Identification of MLKL membrane translocation as a checkpoint in necroptotic cell death using MonobodiesEmma J Petrie, Richard W Birkinshaw, Akiko Koide, et al.
Nature Communications|April 14, 2021
Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosisSarah E Garnish, Yanxiang Meng, Akiko Koide, et al.
Nature Communications|June 23, 2018
Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosisEmma J Petrie, Jarrod J Sandow, Annette V Jacobsen, et al.
Cell Reports|September 26, 2019
Viral MLKL Homologs Subvert Necroptotic Cell Death by Sequestering Cellular RIPK3Emma J Petrie, Jarrod J Sandow, Wil I L Lehmann, et al.
The Biochemical Journal|October 11, 2013
A robust methodology to subclassify pseudokinases based on their nucleotide-binding propertiesJames M Murphy, Qingwei Zhang, Samuel N Young, et al.
Proceedings of the National Academy of Sciences of the United States of America|October 8, 2014
Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell deathJoanne M Hildebrand, Maria C Tanzer, Isabelle S Lucet, et al.
Cell Death & Disease|June 17, 2026
Impact of BECLIN1 haploinsufficiency on goblet cell function and susceptibility to colitisJuliani Juliani, Sharon Tran, Tiffany J Harris, et al.
Pageof 4

Showing results (21-30 of 38) with videos related to

Sort By:
Pageof 4
Nature Communications|October 26, 2023
Phosphorylation-dependent pseudokinase domain dimerization drives full-length MLKL oligomerizationYanxiang Meng, Sarah E Garnish, Katherine A Davies, et al.
The Biochemical Journal|April 28, 2023
The VEGFR/PDGFR tyrosine kinase inhibitor, ABT-869, blocks necroptosis by targeting RIPK1 kinaseCatia L Pierotti, Annette V Jacobsen, Christoph Grohmann, et al.
The Biochemical Journal|September 26, 2025
Unconventional binding of calmodulin to CHK2 kinase inhibits catalytic activityChristopher R Horne, Tingting Wang, Samuel N Young, et al.
Proceedings of the National Academy of Sciences of the United States of America|April 3, 2020
Identification of MLKL membrane translocation as a checkpoint in necroptotic cell death using MonobodiesEmma J Petrie, Richard W Birkinshaw, Akiko Koide, et al.
Nature Communications|April 14, 2021
Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosisSarah E Garnish, Yanxiang Meng, Akiko Koide, et al.
Nature Communications|June 23, 2018
Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosisEmma J Petrie, Jarrod J Sandow, Annette V Jacobsen, et al.
Cell Reports|September 26, 2019
Viral MLKL Homologs Subvert Necroptotic Cell Death by Sequestering Cellular RIPK3Emma J Petrie, Jarrod J Sandow, Wil I L Lehmann, et al.
The Biochemical Journal|October 11, 2013
A robust methodology to subclassify pseudokinases based on their nucleotide-binding propertiesJames M Murphy, Qingwei Zhang, Samuel N Young, et al.
Proceedings of the National Academy of Sciences of the United States of America|October 8, 2014
Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell deathJoanne M Hildebrand, Maria C Tanzer, Isabelle S Lucet, et al.
Cell Death & Disease|June 17, 2026
Impact of BECLIN1 haploinsufficiency on goblet cell function and susceptibility to colitisJuliani Juliani, Sharon Tran, Tiffany J Harris, et al.
Pageof 4