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Molecular Biology of the Cell|March 11, 2011
Nuclear envelope dispersion triggered by deregulated Cdk5 precedes neuronal deathKuei-Hua Chang, Parminder Singh Multani, Kai-Hui Sun, et al.
Scientific Reports|January 25, 2024
Transcriptional characterization of iPSC-derived microglia as a model for therapeutic development in neurodegenerationGokul Ramaswami, Yeliz Yuva-Aydemir, Brynn Akerberg, et al.
ACS Medicinal Chemistry Letters|November 20, 2024
Cyclic Peptide C5aR1 Antagonist Design Using Solution Conformational Analysis Derived from Residual Dipolar CouplingsKathleen A Farley, Ye Che, Ricardo Lira, et al.
Protein Science : a Publication of the Protein Society|September 24, 2017
The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibitionJustin Hall, Erik C Ralph, Suman Shanker, et al.
Bioorganic & Medicinal Chemistry Letters|August 4, 2015
Identification of orally-bioavailable antagonists of the TRPV4 ion-channelZhi-Liang Wei, Margaret T Nguyen, Donogh J R O'Mahony, et al.
European Journal of Medicinal Chemistry|January 20, 2018
Rational approach to highly potent and selective apoptosis signal-regulating kinase 1 (ASK1) inhibitorsFrank Lovering, Paul Morgan, Christophe Allais, et al.
Annals of the New York Academy of Sciences|September 30, 2022
Engineering multicellular living systems-a Keystone Symposia reportJennifer Cable, Paola Arlotta, Kevin Kit Parker, et al.
ACS Chemical Biology|September 24, 2024
Discovery, Characterization, and Structure of a Cell Active PAD2 Inhibitor Acting through a Novel Allosteric MechanismLaura J Byrnes, Won Young Choi, Paul Balbo, et al.
Cell Reports|June 9, 2021
Human amyotrophic lateral sclerosis excitability phenotype screen: Target discovery and validationXuan Huang, Kasper C D Roet, Liying Zhang, et al.
Bioorganic & Medicinal Chemistry|April 8, 2020
Design and optimization of a series of 4-(3-azabicyclo[3.1.0]hexan-3-yl)pyrimidin-2-amines: Dual inhibitors of TYK2 and JAK1Andrew Fensome, Catherine M Ambler, Eric Arnold, et al.
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