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Journal of Medicinal Chemistry
|
March 3, 2012
Discovery of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors: structure-based design and in vivo reduction of amyloid β-peptides
Heinrich Rueeger, Rainer Lueoend, Olivier Rogel, et al.
Journal of Neurochemistry
|
April 12, 2006
Hyperdopaminergia and altered locomotor activity in GABAB1-deficient mice
Claire-Marie Vacher, Martin Gassmann, Sandrine Desrayaud, et al.
Bioorganic & Medicinal Chemistry
|
October 16, 2014
AFQ056/mavoglurant, a novel clinically effective mGluR5 antagonist: identification, SAR and pharmacological characterization
Ivo Vranesic, Silvio Ofner, Peter Josef Flor, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
|
March 24, 2015
Micropreparative isolation and NMR structure elucidation of metabolites of the drug candidate 1-isopropyl-4-(4-isopropylphenyl)-6-(prop-2-yn-1-yloxy) quinazolin-2(1H)-one from rat bile and urine
Joachim Blanz, Thierry Délémonté, David Pearson, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 29, 2013
Discovery of cyclic sulfoxide hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors: structure based design and in vivo reduction of amyloid β-peptides
Heinrich Rueeger, Rainer Lueoend, Rainer Machauer, et al.
Chemmedchem
|
November 19, 2016
Design and Synthesis of Selurampanel, a Novel Orally Active and Competitive AMPA Receptor Antagonist
David Orain, Engin Tasdelen, Samuel Haessig, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems
|
January 5, 2018
Utility of food pellets containing 1-aminobenzotriazole for longer term in vivo inhibition of cytochrome P450 in mice
Rowan Stringer, Valerie Cordier, Catherine Afatsawo, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 7, 2009
Macrocyclic peptidomimetic beta-secretase (BACE-1) inhibitors with activity in vivo
Rainer Machauer, Kurt Laumen, Siem Veenstra, et al.
Acta Neuropathologica Communications
|
February 17, 2018
Brain region-specific enhancement of remyelination and prevention of demyelination by the CSF1R kinase inhibitor BLZ945
Nicolau Beckmann, Elisa Giorgetti, Anna Neuhaus, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 27, 2011
6-Amino quinazolinedione sulfonamides as orally active competitive AMPA receptor antagonists
David Orain, Silvio Ofner, Manuel Koller, et al.
Page
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Search research articles
Search
Showing results (21-30 of 35) with videos related to
Sort By:
Page
of 4
Journal of Medicinal Chemistry
|
March 3, 2012
Discovery of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors: structure-based design and in vivo reduction of amyloid β-peptides
Heinrich Rueeger, Rainer Lueoend, Olivier Rogel, et al.
Journal of Neurochemistry
|
April 12, 2006
Hyperdopaminergia and altered locomotor activity in GABAB1-deficient mice
Claire-Marie Vacher, Martin Gassmann, Sandrine Desrayaud, et al.
Bioorganic & Medicinal Chemistry
|
October 16, 2014
AFQ056/mavoglurant, a novel clinically effective mGluR5 antagonist: identification, SAR and pharmacological characterization
Ivo Vranesic, Silvio Ofner, Peter Josef Flor, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
|
March 24, 2015
Micropreparative isolation and NMR structure elucidation of metabolites of the drug candidate 1-isopropyl-4-(4-isopropylphenyl)-6-(prop-2-yn-1-yloxy) quinazolin-2(1H)-one from rat bile and urine
Joachim Blanz, Thierry Délémonté, David Pearson, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 29, 2013
Discovery of cyclic sulfoxide hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors: structure based design and in vivo reduction of amyloid β-peptides
Heinrich Rueeger, Rainer Lueoend, Rainer Machauer, et al.
Chemmedchem
|
November 19, 2016
Design and Synthesis of Selurampanel, a Novel Orally Active and Competitive AMPA Receptor Antagonist
David Orain, Engin Tasdelen, Samuel Haessig, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems
|
January 5, 2018
Utility of food pellets containing 1-aminobenzotriazole for longer term in vivo inhibition of cytochrome P450 in mice
Rowan Stringer, Valerie Cordier, Catherine Afatsawo, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 7, 2009
Macrocyclic peptidomimetic beta-secretase (BACE-1) inhibitors with activity in vivo
Rainer Machauer, Kurt Laumen, Siem Veenstra, et al.
Acta Neuropathologica Communications
|
February 17, 2018
Brain region-specific enhancement of remyelination and prevention of demyelination by the CSF1R kinase inhibitor BLZ945
Nicolau Beckmann, Elisa Giorgetti, Anna Neuhaus, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 27, 2011
6-Amino quinazolinedione sulfonamides as orally active competitive AMPA receptor antagonists
David Orain, Silvio Ofner, Manuel Koller, et al.
Page
of 4