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Biochemical Pharmacology|May 6, 2026
Pharmacological targeting of cholesterol biosynthesis in cancer: Sterol intermediates, oxysterols, and sterol flux rewiringPhilippe de Médina, Julio Buñay, Silia Ayadi, et al.Ageing Research Reviews|November 28, 2025
Liver X receptors and the hallmarks of aging: From molecular mechanisms to therapeutic opportunitiesMarc Poirot, Julio Buñay, Silia Ayadi, et al.Autophagy|September 5, 2022
Targeting NR1H/liver X receptor with dendrogenin A differentiates tumor cells to activate a new secretory pathway releasing immunogenic anti-tumor vesicles enriched in LC3-II-associated exosomesPhilippe de Medina, Julio Bunay, Marc Poirot, et al.Proceedings of the National Academy of Sciences of the United States of America|July 10, 2010
Identification and pharmacological characterization of cholesterol-5,6-epoxide hydrolase as a target for tamoxifen and AEBS ligandsPhilippe de Medina, Michael R Paillasse, Gregory Segala, et al.Journal of Medicinal Chemistry|October 14, 2009
Synthesis of new alkylaminooxysterols with potent cell differentiating activities: identification of leads for the treatment of cancer and neurodegenerative diseasesPhilippe de Medina, Michael R Paillasse, Bruno Payré, et al.The Journal of Pharmacology and Experimental Therapeutics|July 13, 2006
The prototypical inhibitor of cholesterol esterification, Sah 58-035 [3-[decyldimethylsilyl]-n-[2-(4-methylphenyl)-1-phenylethyl]propanamide], is an agonist of estrogen receptorsPhilippe de Medina, Nadia Boubekeur, Patrick Balaguer, et al.Seminars in Cancer Biology|March 16, 2026
Oxysterols at the Crossroads of Cholesterol Metabolism and CancerJulio Buñay, Silia Ayadi, Chloe Gressein, et al.Journal of Lipid Research|January 31, 2012
Surprising unreactivity of cholesterol-5,6-epoxides towards nucleophilesMichael R Paillasse, Nathalie Saffon, Heinz Gornitzka, et al.Frontiers in Aging Neuroscience|August 11, 2015
Dendrogenin A and B two new steroidal alkaloids increasing neural responsiveness in the deafened guinea pigAnette Fransson, Philippe de Medina, Michaël R Paillasse, et al.Journal of Lipid Research|June 9, 2009
Signaling through cholesterol esterification: a new pathway for the cholecystokinin 2 receptor involved in cell growth and invasionMichael R Paillasse, Philippe de Medina, Guillaume Amouroux, et al.Pageof 8