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Molecular Therapy. Oncology|July 1, 2025
Boosting anti-tumor immunity with TILT-517 oncolytic adenovirus and checkpoint blockade in renal cell carcinomaVictor Arias, Tatiana V Kudling, James H A Clubb, et al.Journal for Immunotherapy of Cancer|January 27, 2025
Transient lymphocyte count decrease correlates with oncolytic adenovirus efficacy in humans: mechanistic and biomarker findings from TUNIMO phase I trialSanteri A Pakola, James H A Clubb, Tatiana V Kudling, et al.Cancer Gene Therapy|April 10, 2025
Single-cell profiling of peripheral blood mononuclear cells from patients treated with oncolytic adenovirus TILT-123 reveals baseline immune status as a predictor of therapy outcomesTatiana V Kudling, Dmitrii Bychkov, James H A Clubb, et al.Cancer Immunology, Immunotherapy : CII|June 4, 2025
Oncolytic adenovirus encoding variant interleukin-2 combined with chemotherapy enables PD-L1 inhibition in pancreatic cancer modelsSanteri A Pakola, Nea Ojala, Tatiana V Kudling, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|March 28, 2024
Safety, Efficacy, and Biological Data of T-Cell-Enabling Oncolytic Adenovirus TILT-123 in Advanced Solid Cancers from the TUNIMO Monotherapy Phase I TrialSanteri A Pakola, Katriina J Peltola, James H A Clubb, et al.Journal of Experimental & Clinical Cancer Research : CR|November 7, 2024
Single intravenous administration of oncolytic adenovirus TILT-123 results in systemic tumor transduction and immune response in patients with advanced solid tumorsElise Jirovec, Dafne C A Quixabeira, James H A Clubb, et al.Molecular Therapy : the Journal of the American Society of Gene Therapy|May 15, 2026
Fully intravenous split-dose administration of the oncolytic adenovirus TILT-123 in advanced solid tumorsElise Jirovec, Katriina J Jalkanen, Dafne C A Quixabeira, et al.Cell Reports. Medicine|March 19, 2025
Safety and efficacy of combined treatment with tumor-infiltrating lymphocytes and oncolytic adenovirus TILT-123 in metastatic melanomaTine J Monberg, Santeri A Pakola, Benedetta Albieri, et al.Pageof 1