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The Prostate|April 15, 2024
Characterization of structural, biochemical, pharmacokinetic, and pharmacodynamic properties of the LSD1 inhibitor bomedemstat in preclinical modelsSumer Jasmine, Adel Mandl, Timothy E G Krueger, et al.Nature Communications|September 5, 2024
The scaffolding function of LSD1 controls DNA methylation in mouse ESCsSandhya Malla, Kanchan Kumari, Carlos A García-Prieto, et al.Antiviral Research|December 1, 2009
Structure and functionality in flavivirus NS-proteins: perspectives for drug designMichela Bollati, Karin Alvarez, René Assenberg, et al.Biorxiv : the Preprint Server for Biology|May 27, 2024
Asymmetric Engagement of Dimeric CRL3 KBTBD4 by the Molecular Glue UM171 Licenses Degradation of HDAC1/2 ComplexesMegan Jr Yeo, Olivia Zhang, Xiaowen Xie, et al.Science Advances|March 27, 2026
A synergistic interaction between PRMT5 and LSD1 inhibitors in AMLNesteene Joy Param, Elisa Arceci, Francesco Fiorentino, et al.Nature|February 12, 2025
UM171 glues asymmetric CRL3-HDAC1/2 assembly to degrade CoREST corepressorsMegan J R Yeo, Olivia Zhang, Xiaowen Xie, et al.Nature Communications|January 6, 2018
Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitorsJay H Kalin, Muzhou Wu, Andrea V Gomez, et al.Biorxiv : the Preprint Server for Biology|April 3, 2026
AI-Enhanced Adaptive Virtual Screening Platform Enabling Exploration of 69 Billion Molecules Discovers Structurally Validated FSP1 InhibitorsDomiziana Cecchini, AkshatKumar Nigam, Ming Tang, et al.Pageof 20