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Nature Microbiology|July 15, 2020
Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitorsManuel Saldivia, Eric Fang, Xiaolei Ma, et al.
Journal of Medicinal Chemistry|January 29, 2019
Optimization of Fused Bicyclic Allosteric SHP2 InhibitorsJeffrey T Bagdanoff, Zhouliang Chen, Michael Acker, et al.
ACS Chemical Biology|January 6, 2018
Dual Allosteric Inhibition of SHP2 PhosphataseMichelle Fodor, Edmund Price, Ping Wang, et al.
Journal of Medicinal Chemistry|January 29, 2019
6-Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 InhibitorsPatrick Sarver, Michael Acker, Jeffrey T Bagdanoff, et al.
Journal of Medicinal Chemistry|June 28, 2016
Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase InhibitorJorge Garcia Fortanet, Christine Hiu-Tung Chen, Ying-Nan P Chen, et al.
Journal of Medicinal Chemistry|April 30, 2021
Discovery and Optimization of DNA Gyrase and Topoisomerase IV Inhibitors with Potent Activity against Fluoroquinolone-Resistant Gram-Positive BacteriaGuillaume Lapointe, Colin K Skepper, Lauren M Holder, et al.
Journal of Medicinal Chemistry|July 8, 2020
Topoisomerase Inhibitors Addressing Fluoroquinolone Resistance in Gram-Negative BacteriaColin K Skepper, Duncan Armstrong, Carl J Balibar, et al.
Journal of Medicinal Chemistry|September 10, 2020
Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of CancerMatthew J LaMarche, Michael Acker, Andreea Argintaru, et al.
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