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Molecular Neurobiology|May 15, 2026
Amyloid Plaques Ameliorate Memory Deficits and Hippocampal Neuron Loss in an Aβ4-42-Driven Alzheimer's Disease Mouse ModelSilvia Zampar, Merle Fricke, Florian Kremser, et al.Experimental Cell Research|June 19, 2008
Increased AICD generation does not result in increased nuclear translocation or activation of target gene transcriptionElaine Waldron, Simone Isbert, Andreas Kern, et al.Life (Basel, Switzerland)|April 28, 2023
Brain Region-Specific Differences in Amyloid-β Plaque Composition in 5XFAD MiceAngelika Sabine Bader, Marius-Uwe Gnädig, Merle Fricke, et al.The Journal of Biological Chemistry|March 7, 2008
The functional role of the second NPXY motif of the LRP1 beta-chain in tissue-type plasminogen activator-mediated activation of N-methyl-D-aspartate receptorsAnne M Martin, Christoph Kuhlmann, Svenja Trossbach, et al.Bioorganic & Medicinal Chemistry Letters|January 11, 2015
SAR-studies of γ-secretase modulators with PPARγ-agonistic and 5-lipoxygenase-inhibitory activity for Alzheimer's diseaseDaniel Flesch, Julia Ness, Christina Lamers, et al.Cellular and Molecular Life Sciences : CMLS|October 27, 2009
Inactivation of the proximal NPXY motif impairs early steps in LRP1 biosynthesisSara M Reekmans, Thorsten Pflanzner, Philip L S M Gordts, et al.The Journal of Biological Chemistry|August 27, 2011
Substrate sequence influences γ-secretase modulator activity, role of the transmembrane domain of the amyloid precursor proteinSarah A Sagi, Christian B Lessard, Kellen D Winden, et al.The Journal of Biological Chemistry|July 2, 2023
Pathogenic Aβ production by heterozygous PSEN1 mutations is intrinsic to the mutant protein and not mediated by conformational hindrance of wild-type PSEN1Vanessa Kurth, Isabella Ogorek, Carolina Münch, et al.Journal of Neurochemistry|October 7, 2009
alpha-secretase mediated conversion of the amyloid precursor protein derived membrane stub C99 to C83 limits Abeta generationSebastian Jäger, Stefanie Leuchtenberger, Anne Martin, et al.Journal of Neuropathology and Experimental Neurology|December 6, 2003
Epigenetic silencing of the HIC-1 gene in human medulloblastomasAnke Waha, Andreas Waha, Arend Koch, et al.Pageof 8