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Sathesh Bhat

Showing results (11-20 of 23) with videos related to

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Bioorganic & Medicinal Chemistry Letters|October 12, 2010
2-Aryl benzimidazoles: human SCD1-specific stearoyl coenzyme-A desaturase inhibitorsDavid A Powell, Yeeman Ramtohul, Marie-Eve Lebrun, et al.
Proceedings of the National Academy of Sciences of the United States of America|March 16, 2016
Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in ratsGeraldine Harriman, Jeremy Greenwood, Sathesh Bhat, et al.
Journal of Chemical Information and Modeling|January 24, 2007
Solvated interaction energy (SIE) for scoring protein-ligand binding affinities. 1. Exploring the parameter spaceMarwen Naïm, Sathesh Bhat, Kathryn N Rankin, et al.
Journal of Chemical Information and Modeling|April 13, 2022
AutoDesigner, a <i>De Novo</i> Design Algorithm for Rapidly Exploring Large Chemical Space for Lead Optimization: Application to the Design and Synthesis of d-Amino Acid Oxidase InhibitorsPieter H Bos, Evelyne M Houang, Fabio Ranalli, et al.
Nature Communications|August 26, 2025
Harnessing free energy calculations for kinome-wide selectivity in drug discovery campaigns with a Wee1 case studyJennifer Lynn Knight, Anthony J Clark, Jiashi Wang, et al.
Journal of Chemical Information and Modeling|October 3, 2024
AutoDesigner - Core Design, a De Novo Design Algorithm for Chemical Scaffolds: Application to the Design and Synthesis of Novel Selective Wee1 InhibitorsPieter H Bos, Fabio Ranalli, Emelie Flood, et al.
Nature Medicine|September 20, 2016
Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical modelsRobert U Svensson, Seth J Parker, Lillian J Eichner, et al.
Journal of Medicinal Chemistry|October 13, 2025
Accelerated <i>In Silico</i> Discovery of <b>SGR-1505</b>: A Potent MALT1 Allosteric Inhibitor for the Treatment of Mature B-Cell MalignanciesZhe Nie, Michael Trzoss, Andrew T Placzek, et al.
Journal of Medicinal Chemistry|December 12, 2024
Discovery of a Novel Mutant-Selective Epidermal Growth Factor Receptor Inhibitor Using an <i>In Silico</i> Enabled Drug Discovery PlatformHideyuki Igawa, Zef A Konst, Eric Therrien, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Novel Quinoline-Based P2-P4 Macrocyclic Derivatives As Pan-Genotypic HCV NS3/4a Protease InhibitorsUnmesh Shah, Charles Jayne, Samuel Chackalamannil, et al.
Pageof 3

Showing results (11-20 of 23) with videos related to

Sort By:
Pageof 3
Bioorganic & Medicinal Chemistry Letters|October 12, 2010
2-Aryl benzimidazoles: human SCD1-specific stearoyl coenzyme-A desaturase inhibitorsDavid A Powell, Yeeman Ramtohul, Marie-Eve Lebrun, et al.
Proceedings of the National Academy of Sciences of the United States of America|March 16, 2016
Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in ratsGeraldine Harriman, Jeremy Greenwood, Sathesh Bhat, et al.
Journal of Chemical Information and Modeling|January 24, 2007
Solvated interaction energy (SIE) for scoring protein-ligand binding affinities. 1. Exploring the parameter spaceMarwen Naïm, Sathesh Bhat, Kathryn N Rankin, et al.
Journal of Chemical Information and Modeling|April 13, 2022
AutoDesigner, a <i>De Novo</i> Design Algorithm for Rapidly Exploring Large Chemical Space for Lead Optimization: Application to the Design and Synthesis of d-Amino Acid Oxidase InhibitorsPieter H Bos, Evelyne M Houang, Fabio Ranalli, et al.
Nature Communications|August 26, 2025
Harnessing free energy calculations for kinome-wide selectivity in drug discovery campaigns with a Wee1 case studyJennifer Lynn Knight, Anthony J Clark, Jiashi Wang, et al.
Journal of Chemical Information and Modeling|October 3, 2024
AutoDesigner - Core Design, a De Novo Design Algorithm for Chemical Scaffolds: Application to the Design and Synthesis of Novel Selective Wee1 InhibitorsPieter H Bos, Fabio Ranalli, Emelie Flood, et al.
Nature Medicine|September 20, 2016
Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical modelsRobert U Svensson, Seth J Parker, Lillian J Eichner, et al.
Journal of Medicinal Chemistry|October 13, 2025
Accelerated <i>In Silico</i> Discovery of <b>SGR-1505</b>: A Potent MALT1 Allosteric Inhibitor for the Treatment of Mature B-Cell MalignanciesZhe Nie, Michael Trzoss, Andrew T Placzek, et al.
Journal of Medicinal Chemistry|December 12, 2024
Discovery of a Novel Mutant-Selective Epidermal Growth Factor Receptor Inhibitor Using an <i>In Silico</i> Enabled Drug Discovery PlatformHideyuki Igawa, Zef A Konst, Eric Therrien, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Novel Quinoline-Based P2-P4 Macrocyclic Derivatives As Pan-Genotypic HCV NS3/4a Protease InhibitorsUnmesh Shah, Charles Jayne, Samuel Chackalamannil, et al.
Pageof 3