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Journal of Environmental Radioactivity|June 22, 2014
Measurement of air dose rates over a wide area around the Fukushima Dai-ichi Nuclear Power Plant through a series of car-borne surveysMasaki Andoh, Yukio Nakahara, Shuichi Tsuda, et al.Cell Transplantation|October 26, 2020
Investigation of Clinical Safety of Human iPS Cell-Derived Liver Organoid Transplantation to Infantile Patients in Porcine ModelTomonori Tsuchida, Soichiro Murata, Shunsuke Hasegawa, et al.Journal of Medicinal Chemistry|March 21, 2012
Discovery of phenylpropanoic acid derivatives containing polar functionalities as potent and orally bioavailable G protein-coupled receptor 40 agonists for the treatment of type 2 diabetesSatoshi Mikami, Shuji Kitamura, Nobuyuki Negoro, et al.Journal of Medicinal Chemistry|August 11, 2017
Discovery of Clinical Candidate N-((1S)-1-(3-Fluoro-4-(trifluoromethoxy)phenyl)-2-methoxyethyl)-7-methoxy-2-oxo-2,3-dihydropyrido[2,3-b]pyrazine-4(1H)-carboxamide (TAK-915): A Highly Potent, Selective, and Brain-Penetrating Phosphodiesterase 2A Inhibitor for the Treatment of Cognitive DisordersSatoshi Mikami, Shinji Nakamura, Tomoko Ashizawa, et al.Chemical & Pharmaceutical Bulletin|November 3, 2017
Discovery of a Novel Series of Pyrazolo[1,5-a]pyrimidine-Based Phosphodiesterase 2A Inhibitors Structurally Different from N-((1S)-1-(3-Fluoro-4-(trifluoromethoxy)phenyl)-2-methoxyethyl)-7-methoxy-2-oxo-2,3-dihydropyrido[2,3-b]pyrazine-4(1H)-carboxamide (TAK-915), for the Treatment of Cognitive DisordersSatoshi Mikami, Masanori Kawasaki, Shuhei Ikeda, et al.Journal of Medicinal Chemistry|April 12, 2012
Optimization of (2,3-dihydro-1-benzofuran-3-yl)acetic acids: discovery of a non-free fatty acid-like, highly bioavailable G protein-coupled receptor 40/free fatty acid receptor 1 agonist as a glucose-dependent insulinotropic agentNobuyuki Negoro, Shinobu Sasaki, Satoshi Mikami, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of TAK-875: A Potent, Selective, and Orally Bioavailable GPR40 AgonistNobuyuki Negoro, Shinobu Sasaki, Satoshi Mikami, et al.American Journal of Physiology. Renal Physiology|January 25, 2013
Retention of fetuin-A in renal tubular lumen protects the kidney from nephrocalcinosis in ratsIsao Matsui, Takayuki Hamano, Satoshi Mikami, et al.Journal of Medicinal Chemistry|February 21, 2022
Discovery of Brain-Penetrant Glucosylceramide Synthase Inhibitors with a Novel PharmacophoreYuta Tanaka, Masaki Seto, Keiko Kakegawa, et al.Pageof 6