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The Journal of Biological Chemistry|August 21, 2013
FRAX597, a small molecule inhibitor of the p21-activated kinases, inhibits tumorigenesis of neurofibromatosis type 2 (NF2)-associated SchwannomasSilvia Licciulli, Jasna Maksimoska, Chun Zhou, et al.
Elife|May 21, 2014
Pak2 is required for actin cytoskeleton remodeling, TCR signaling, and normal thymocyte development and maturationHyewon Phee, Byron B Au-Yeung, Olga Pryshchep, et al.
Biorxiv : the Preprint Server for Biology|July 10, 2023
Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpointsAlexa C Cannon, Konstantin Budagyan, Cristina Uribe-Alvarez, et al.
Oncogene|January 19, 2024
Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpointsAlexa C Cannon, Konstantin Budagyan, Cristina Uribe-Alvarez, et al.
Breast Cancer Research and Treatment|June 30, 2019
Combined inhibition of Aurora A and p21-activated kinase 1 as a new treatment strategy in breast cancerVladislav Korobeynikov, Michelle Borakove, Yayi Feng, et al.
Oncotarget|October 15, 2016
Reduced PAK1 activity sensitizes FA/BRCA-proficient breast cancer cells to PARP inhibitionOlga Villamar Cruz, Tatiana Y Prudnikova, Daniela Araiza-Olivera, et al.
Nucleic Acids Research|September 22, 2023
The TRIM69-MST2 signaling axis regulates centrosome dynamics and chromosome segregationYilin Wang, Patrik Risteski, Yang Yang, et al.
Cell|May 22, 2003
Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinaseWang L Cheung, Kozo Ajiro, Kumiko Samejima, et al.
Oncotarget|January 19, 2015
Group I Paks as therapeutic targets in NF2-deficient meningiomaHoi-Yee Chow, Biao Dong, Sergio G Duron, et al.
Cell Reports|March 25, 2025
KRAS G12V mutation-selective requirement for ACSS2 in colorectal adenoma formationKonstantin Budagyan, Alexa C Cannon, Adam Chatoff, et al.
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